Integrating HIV Prevention With TB Household Contact Evaluation in Uganda
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Home-based HIV self-testing, Home-based initiation of PrEP.
- Who it may be relevant to
- Registry conditions: Tuberculosis (TB), Human Immunodeficiency Virus (HIV) Prophylaxis. Basic parameters: from 15 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Uganda
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Integrating HIV Prevention With TB Household Contact Evaluation in Uganda (TB PrEP)
Overview
This household randomized implementation study assesses the implementation and effectiveness of home-based HIV self- testing and PrEP initiation versus standard clinic referral for PrEP initiation during modified standard-of-care (modified SOC) household TB contact investigation in Uganda. It uses qualitative methods to evaluate the process of implementing the intervention and a health economic evaluation to assess the financial sustainability of this strategy.
Interventions
- Other Home-based HIV self-testing
Integration of HIV self-testing into TB household contact investigation - Other Home-based initiation of PrEP
Integration of PrEP initiation into TB household contact investigation
Primary outcome measures
- PrEP uptake [Time frame: From enrollment to the one-month follow-up visit]
Secondary outcome measures (2)
- PrEP continuation [Time frame: From enrollment to six-month follow-up visit]
- HIV testing coverage [Time frame: From enrollment to six-month follow-up visit]
Eligibility criteria
Inclusion criteria
- Person with pulmonary TB OR live in a household with someone with pulmonary TB being treated at one of the participating health facilities
- Household includes ≥2 persons
- Age 15 years and older
- Willingness to participate in study procedures
Exclusion criteria
- Lives in a congregate setting (e.g., dormitory or jail)
- Lives outside the study area
- Any other condition that, in the opinion of the Investigator/designee, could preclude informed consent, make study participation unsafe, or otherwise interfere with achieving study objectives
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Prevention
Study locations
Uganda · 1 center
- Infectious Diseases Institute — Kampala
Identifiers
NCT: NCT07119359 · STUDY00020907 · R01MH134685