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Recruiting NCT07112001

A Behavioral mHealth Intervention for People With HIV With Anxiety and Depression

No phase Interventional HIV Depression Anxiety

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: PositiveLinks with Counseling, Standard of Care (SOC).
Who it may be relevant to
Registry conditions: HIV, Depression, Anxiety. Basic parameters: 18 years — 90 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Adaptation and Implementation of a Behavioral mHealth Intervention to Reduce Anxiety and Depression and End the HIV Epidemic in the Rural South

Overview

This study will adapt and assess the preliminary effectiveness of a community health worker-delivered mental health counselling intervention delivered remotely to reduce anxiety and depression among people with HIV in Florida.

Detailed description

The investigators will conduct a pilot randomized controlled trial to evaluate the preliminary effectiveness of an adapted community health worker (CWH)-delivered positive affect counselling intervention delivered remotely via mHealth. The adapted intervention will include CHW-delivered positive affect skill-based counseling accessible through video call that will be accessible through the mHealth app. The CHW will conduct approximately 5 weekly individual 60-minute counseling sessions via a secure video call feature. If the participant does not have symptomatic improvement, the CHW will refer the participant to a licensed mental health professional. Participants will be randomized to receive access to the counselling intervention that also includes modified features of the mHealth app with increased mental health resources (intervention arm) or to current standard of mental health care that includes the unmodified version of the app (control arm). Participants allocated to the intervention arm will receive the counseling intervention approximately weekly for 5 weeks. The study will continue to abstract data from participants' EMR and mHealth app for approximately 6 months after enrollment. To assess preliminary effectiveness, the investigators will analyze differences by condition in anxiety and depression (primary outcome). Informed consent will be obtained prior to study participation.

Interventions

  • Behavioral PositiveLinks with Counseling
    A community health worker delivered, specialized counseling intervention through video call on the PositiveLinks app
  • Behavioral Standard of Care (SOC)
    This intervention includes the use of the unmodified PositiveLinks app and the standard of care for addressing anxiety and depression in the HIV clinic

Primary outcome measures

  • Reduction in Depression [Time frame: 3 months]
  • Reduction in Anxiety [Time frame: 3 months]

Eligibility criteria

Inclusion criteria

  • HIV diagnosis
  • GAD-7 score of 5 or greater
  • PHQ-8 score of 5 or greater

Exclusion criteria

  • Active psychosis
  • Suicidal ideation

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Supportive care

Study locations

United States · 1 center
  • University of Florida — Gainesville

Identifiers

NCT: NCT07112001 · 202003223 · K23MH131463

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗