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Enrolling by invitation NCT07108803

European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis

Observational Infective Endocarditis (IE)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Infective Endocarditis (IE). Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Italy
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis (ERGOSTE)

Overview

The European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis (ERGOSTE) is a nascent large surgical registry that would encompass most relevant aspects of IE in Europe in the contemporary era.

Detailed description

ERGOSTE, Purposes:

* To create a European multicenter retrospective database including a large number of patients undergoing surgical treatment for infective endocarditis (IE). * To perform epidemiologic analyses of IE-patients and involved pathogens. * To find independent predictors of early post-operative death. * To test ALL the scoring systems specifically developed to predict early death after surgery for infective endocarditis. * To devise a specific risk score for early postoperative death. * To explore early and late outcomes of these very difficult patients in order to establish optimal indications, techniques and timing of surgery. * To carry out a number of sub-analyses concerning the demographic parameters and variable clinical presentation of patients, type and severity of cardiac structural involvement, adopted valve prostheses and surgical techniques, and different involved microbiologic agents. * To lay experiential foundations of a prospective database on the topic.

Primary outcome measures

  • Early post-operative mortality [Time frame: Mortality at 1 year after surgery]

Eligibility criteria

Inclusion criteria

  • Patients undergoing cardiac surgery due to infective endocarditis

Exclusion criteria

  • Patients under 18 years

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Italy · 1 center
  • Cardiac Surgery Unit - ASUGI — Trieste

Identifiers

NCT: NCT07108803 · 386_2024

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗