Menu
Not yet recruiting NCT07106281

Chronic Grape Extract in Crosstraining Athletes: A Randomized Crossover Trial

No phase Interventional Performance

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Grape Seed Extract, Placebo.
Who it may be relevant to
Registry conditions: Performance. Basic parameters: 18 years — 35 years · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Spain
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Effect of Chronic Grape Extract Supplementation in Trained Cross-training Athletes: A Randomized, Triple-blinded, Placebo-Controlled Crossover Study

Overview

The aim of this study is to investigate the effect of cronic GSE intake in crosstraining may have a favorable impact on biochemical markers, recovery, and performance.

Detailed description

Supplementation with certain antioxidant nutrients is a feasible strategy to accelerate recovery from fatigue and prevent exercise-induced oxidative damage. Grape seed extract (GSE) contains flavonoids such as proanthocyanidins, which are potent antioxidants with numerous health benefits. Therefore, optimizing the recovery process after training is essential for athletes engaged in strength and power sports who aim to enhance performance.

Thirty trained CrossFit athletes consumed grape seed extract or a placebo for one week. The training session consisted of a 12-minute strength block, a 13-minute metabolic conditioning (MetCon), and a final 15-minute MetCon. The Rating of Perceived Exertion (RPE), Gastrointestinal Distress Score (GDS), blood pressure and the Perceived Recovery Status scale (RPS) were administered at the beginning of the session and at the end of each segment of the CrossFit session. DOMS was assessed using a visual analog scale at 24 and 48 hours after the CrossFit session.

Interventions

  • Dietary supplement Grape Seed Extract
    600mg of Grape Seed Extract
  • Dietary supplement Placebo
    Placebo

Primary outcome measures

  • Performance [Time frame: 48 hours]
  • Performance [Time frame: 60 minutes]
Secondary outcome measures (11)
  • Attention [Time frame: 60 minutes]
  • Performance: Weight used in the crosstraining session [Time frame: 60 minutes]
  • Performance: Time performed in the crosstraining session [Time frame: 60 minutes]
  • Subjective fatigue throug the the RPE scale [Time frame: 60 minutes]
  • Gastrointestinal distress [Time frame: 60 minutes]
  • Recovery [Time frame: 60 minutes]
  • Delayed-onset muscle soreness (DOMS) [Time frame: 24 hours]
  • Capillar lactate levels [Time frame: 60 minutes]
  • Heart rate [Time frame: 60 minutes]
  • Blood pressure [Time frame: 60 minutes]
  • Biochemical parameters [Time frame: 48 hours]

Eligibility criteria

Inclusion criteria

  • Age: 18-35 years.
  • Body mass index: 18.5-30 kg/m2.
  • Ability to understand the instructions, objectives, and study protocol.
  • Minimum of 3 years of experience in crosstraining, with at least 6 hours of weekly training over the past 3 months.
  • Resident on the island of Tenerife.

Exclusion criteria

  • History of a significant adverse cardiovascular event, renal insufficiency, cirrhosis, eating disorder, weight control surgical intervention, or type 2 diabetes mellitus.
  • Any chronic pathology in which the intake of nutritional supplements, especially use of antioxidant supplements during the 4 weeks prior to the start of the study.
  • Any condition that, in the investigator's judgment, would impair the ability to participate in the study or represent a personal risk to the participant.
  • Use of medications that may affect the study results.
  • Unstable body weight for 3 months prior to the start of the study (> 4 kg loss or gain in weight).
  • Active tobacco abuse or illicit drug use, or history of treatment for alcohol abuse.
  • On a special diet or prescribed for other reasons (e.g., celiac disease).

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Crossover
Masking
Quadruple blind
Primary purpose
Other

Study locations

Spain · 1 center
  • Universidad de la Laguna — Santa Cruz de Tenerife

Identifiers

NCT: NCT07106281 · CROSSUVA

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗