Effect of Expiratory Muscle Strength in Patients With Bronchiectasis
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Bronchiectasis. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effect of Expiratory Muscle Strength on Hospital Admission, Disease Severity and Quality of Life in Patients With Bronchiectasis
Overview
This study investigates the relationship between expiratory muscle strength and clinical outcomes such as disease severity, hospital admissions, and quality of life in individuals with bronchiectasis.
Detailed description
This study aims to examine the relationship between expiratory muscle strength and clinical outcomes such as disease severity, hospital admission history, and quality of life in individuals with bronchiectasis. Effective coughing is a critical physiological reflex for airway clearance; however, the relationship between expiratory muscle strength and cough effectiveness in the bronchiectasis population has not been clearly established. Identifying expiratory muscle weakness as a potential contributor to increased symptom burden and impaired airway clearance may improve clinical understanding and support the development of targeted physiotherapy interventions. The findings of this study could serve as a foundation for future interventional research in pulmonary rehabilitation and respiratory muscle training for this population.
Primary outcome measures
- Respiratory Muscle Strength [Time frame: Baseline]
Secondary outcome measures (8)
- Modified Medical Research Council Dyspnea Score [Time frame: Baseline]
- Leicester Cough Questionnaire [Time frame: Baseline]
- Bronchiectasis Severity Index [Time frame: Baseline]
- Hospital Anxiety Depression Scale [Time frame: Baseline]
- Fatigue severity scale [Time frame: Baseline]
- Spirometric measurements (Forced vital capacity) [Time frame: Baseline]
- Spirometric measurements (First second forced expiratory volume) [Time frame: Baseline]
- Spirometric measurements (FEV1/FVC ratio) [Time frame: Baseline]
Eligibility criteria
Inclusion criteria
- Having a diagnosis of non-cystic fibrosis bronchiectasis
- Without an acute infection at the time of assessment (confirmed by medical history, serum C-reactive protein levels, chest X-ray and/or HRCT).
- Being between 18 and 65 years of age
Exclusion criteria
- Myopathies
- Stroke (Cerebrovascular accident - CVA)
- Pregnancy
- Unstable cardiac disease
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
Turkey (Türkiye) · 1 center
- Süreyyapaşa Chest Diseases and Chest Surgery Training and Research Hospital — Istanbul
Identifiers
NCT: NCT07104942 · bronchiectasis_expiratory