Cardiac REhabilitation COhort at the Medicine Campus DaVos to invEstigate Recovery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Cardiac Rehabilitation, Heart Failure, Cardiac Arrest (CA), ACS (Acute Coronary Syndrome). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Switzerland
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The RECOVER study, titled Cardiac Rehabilitation Cohort at the Medicine Campus Davos for Exploration of Recovery, is a prospective, non-interventional, monocentric cohort study conducted at the Hochgebirgsklinik Davos. The study is sponsored by Medicine Campus Davos AG and the Kühne Foundation, with an estimated start date in July 2025 and planned completion by December 2034, with the possibility of extension. The principal investigator of the study is PD Dr. David Niederseer from Hochgebirgsklinik Davos, who also represents the study. The research team includes co-investigators such as Prof. Dr. Stefan Blankenberg and Prof. Dr. Andreas Ziegler from Cardio-CARE, Medicine Campus Davos, as well as Dr. Jan Vontobel from Hochgebirgsklinik Davos. The study will enroll patients referred to Hochgebirgsklinik Davos for cardiac rehabilitation who provide informed consent. Cardiac rehabilitation is an evidence-based therapy for patients with heart disease, including those who have undergone cardiac procedures or surgeries. The primary objectives are to evaluate baseline patient characteristics, rehabilitation strategies, predictors of recovery, and clinical outcomes during and after rehabilitation. To support this, a detailed database and biobank will be established to allow for comprehensive phenotyping, extensive clinical assessments, and long-term follow-up. RECOVER seeks to gain translational insights into how patient-specific factors - such as genetics, plasma, digital and clinical biomarkers, and comorbidities - influence long-term clinical outcomes. The goal is to identify modifiable risk factors to optimize individualized therapeutic approaches in cardiac rehabilitation.
Primary outcome measures
- Composite of cardiovascular mortality, non-fatal myocardial infarction, non-fatal stroke, and hospitalization for heart failure [Time frame: Follow-up 1, 5 and 10 years after inclusion]
- Incidence of all-cause rehospitalization post cardiac intervention or surgery [Time frame: Follow-up 1, 5 and 10 years after inclusion]
Secondary outcome measures (5)
- Patient reported quality of life (QoL) [Time frame: Follow-up 1, 5 and 10 years after inclusion]
- Re-surgery / Re-intervention [Time frame: Follow-up 1, 5 and 10 years after inclusion]
- New-Onset Atrial Fibrillation [Time frame: Follow-up 1, 5 and 10 years after inclusion]
- Cognitive Function [Time frame: Follow-up 1, 5 and 10 years after inclusion]
- Functional Capacity [Time frame: Follow-up 1, 5 and 10 years after inclusion]
Eligibility criteria
Inclusion criteria
- Patients undergoing CR at the HGK
- Written informed consent
- Age ≥ 18 years
Exclusion criteria
- Insufficient knowledge of the German language to understand study documents, the interview, or questionnaires interview without translation
- Physical or psychological incapability to participate in the study
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Switzerland · 1 center
- Hochgebirgsklinik Davos — Davos
Identifiers
NCT: NCT07096973 · 2024-02560