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Recruiting NCT07093528

A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD

— Observational Heart Failure With Preserved Ejection Fraction Coronary Microvascular Dysfunction

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Cardiovascular Magnetic Resonance (CMR).
Who it may be relevant to
Registry conditions: Heart Failure With Preserved Ejection Fraction, Coronary Microvascular Dysfunction. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

CMR Substudy of Coronary Sinus Reducer for the Management of Symptomatic Heart Failure With a Preserved Ejection Fraction (HFpEF) Associated With Coronary Microvascular Dysfunction (CMD)

Overview

To evaluate the effect of CS reducer implantation in patients with HFPEF and CMD on myocardial ischemia, measured by stress myocardial perfusion using cardiovascular magnetic resonance (CMR)

Interventions

  • Diagnostic test Cardiovascular Magnetic Resonance (CMR)
    Patients will consent to undergo a 50-minute non-invasive stress perfusion CMR.

Primary outcome measures

  • Change in endocardial:epicardial perfusion ratio [Time frame: Baseline, 6 Months]

Eligibility criteria

Inclusion criteria

  • Age ≥18
  • Enrollment in main CS-reducer HFPEF study IRB# 25-002292

Exclusion criteria

  • Metal implants that are not suitable for MRI
  • Inability or unwillingness of individual to give written informed consent.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United States · 1 center
  • Mayo Clinic — Rochester

Identifiers

NCT: NCT07093528 · 25-005812

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗