Joshi's Step With Buccal Mucosal Graft Urethroplasty in Nearly Obliterated Bulbar Urethral Stricture
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Joshi's step.
- Who it may be relevant to
- Registry conditions: Joshi's Step, Buccal Mucosal Graft, Urethroplasty, Obliterated Bulbar Urethral Stricture. Basic parameters: from 18 years · Male.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Joshi's Step With Buccal Mucosal Graft Urethroplasty in Nearly Obliterated Bulbar Urethral Stricture: A Prospective Study
Overview
This study aims to evaluate the functional and surgical outcome of Joshi's step with buccal graft urethroplasty for the management of nearly obliterated bulbar urethral stricture.
Detailed description
Urethroplasty is a rapidly evolving art that continually improves and reinvents itself. After a century of silence, during which the anastomotic repair was the only solution for approaching the strictured urethra, the 1990s can be considered the Renaissance period for reconstructive urology.
In 2022, Joshi and Kulkarni introduced a new step to the augmented urethroplasty, particularly in patients with extremely narrow strictures where a single augmentation was insufficient. They avoid any resection of the residual native urethral plate, marking the narrowest portion. Then, the edges of the mucosa are reapproximated with interrupted suturing in a proper non-resecting approach.
Interventions
- Procedure Joshi's step
Patients will undergo dorsal onlay buccal mucosal graft urethroplasty with Joshi's step
Primary outcome measures
- Success rate [Time frame: 6 months postoperatively]
Secondary outcome measures (2)
- Urine flow rate [Time frame: 6 months postoperatively]
- The urethral lumen [Time frame: 6 months postoperatively]
Eligibility criteria
Inclusion criteria
- Patients with primary bulbar urethral stricture.
- Patients with non-traumatic bulbar urethral stricture.
- Patients with nearly obliterated bulbar urethral stricture, with the narrowest portion of the stricture is less than 1.5 cm in length.
Exclusion criteria
- Patients with traumatic bulbar urethral stricture.
- Patients with redo bulbar urethral stricture.
- Patients with obliterated bulbar urethral stricture.
- Patients with nearly obliterated long bulbar urethral stricture.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Tanta University — Tanta
Identifiers
NCT: NCT07088198 · 36264PR661/4/24