Not yet recruiting NCT07086859
Alveolar Ridge Preservation Using Autogenous Whole Tooth Graft With 1 %Metformin :A Randomized Controlled Clinical Trial
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: TEST 1, Control.
- Who it may be relevant to
- Registry conditions: Dimensional Changes After Tooth Extraction, Tooth Extraaction, Socket Preservation. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
This study describes a technique used to preserve the bone dimensions after the tooth extraction inorder to facilitate later on the dental implant placement
Detailed description
Socket preservation by type of graft used from the tooth combined with Metformin to enhace the results of the bone formation
Interventions
- Procedure TEST 1
Autogenous whole tooth graft with metformin - Procedure Control
Autogenous whole tooth graft
Primary outcome measures
- Radiographic buccolingual width ridge loss [Time frame: 6 months]
Secondary outcome measures (5)
- Alveolar buccal ridge height, lingual ridge height [Time frame: 6 months]
- the area percentage of newly formed bone, soft tissue and residual graft [Time frame: 6 months]
- Patient satisfaction evaluation [Time frame: 2 weeks]
- Total number of analgesics taken in the first week [Time frame: 1 week]
- Socket wound healing score [Time frame: 2 weeks]
Eligibility criteria
Inclusion criteria
- 18 years or older
- patients requiring single extraction of non-molar tooth
- extraction sockets having more than 50% buccal alveolar bone loss
Exclusion criteria
- Pregnancy
- smokers
- patients not maintaing good oral hygiene
- presernce of acute endodontic infection in the tooth to be ectracted
- medical conditions hindering implant placement
- uncontrolled diabetes
- Immune suppression
- bisphosphanates
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Other
Study locations
Egypt · 1 center
- Cairo Univeristy — Giza
Publications
- Elfana A, El-Kholy S, Saleh HA, Fawzy El-Sayed K. Alveolar ridge preservation using autogenous whole-tooth versus demineralized dentin grafts: A randomized controlled clinical trial. Clin Oral Implants Res. 2021 May;32(5):539-548. doi: 10.1111/clr.13722. Epub 2021 Mar 1. PMID 33565656
Identifiers
NCT: NCT07086859 · 279