Aerobic Exercises and Hemodialysis Patients
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Aerobic Exercises, Conventional Program.
- Who it may be relevant to
- Registry conditions: Hemodialysis. Basic parameters: 40 years — 60 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Impact of Aerobic Exercises on Serum Uric Acid Levels in Hemodialysis Patients
Overview
Patients undergoing hemodialysis (HD) frequently exhibit elevated serum uric acid (SUA) levels, which are associated with cardiovascular risks, joint issues, and diminished quality of life (QoL). Aerobic exercise has been shown to improve cardiovascular health and reduce SUA levels in various populations, suggesting potential benefits for HD patients. Objective: This study aimed to investigate the impact of aerobic exercise on serum uric acid (SUA) levels, functional capacity, and quality of life (QoL) in patients undergoing hemodialysis (HD). Methods: This randomized controlled trial will recruit 32 participants, aged 40-60, undergoing HD. The intervention group (Group A) will participate in a structured 6-week aerobic exercise program, while the control group (Group B) will receive only conventional physical therapy. Pre- and post-intervention assessments included SUA levels, the Six-Minute Walk Test (6MWT), and the Kidney Disease Quality of Life Short Form (KDQOL-SF™)
Detailed description
32 Subjects of both genders will participate in this study at El-khazendara Hospitals with age ranged between (40-60) years old. They will receive a comprehensive verbal and written explanation of the study, including its objectives, procedures, and potential benefits.
participants will randomly assigned into two equal groups using a sealed-envelope randomization method to ensure unbiased allocation.
* Group A (study Group): 16 HD patients receiving a conventional physical therapy program (breathing, stretching, and lower limb circulatory exercises) plus the aerobic exercise program. * Group B (Control Group): 16 HD patients receiving only the conventional physical therapy program.
6-weeks of aerobic exercise program (3 sessions per week, 20-45 minutes each session)
Outcome measures include:
* Serum Uric Acid: Measured using an automated biochemistry analyzer, with results reported in mg/dL. * Functional Capacity: Assessed using the Six-Minute Walk Test (6MWT), a validated tool used to evaluate exercise tolerance and endurance in clinical populations. * Quality of Life:Measured using the Kidney Disease Quality of Life Short Form (KDQOL-SF™) Arabic Version, which assesses various domains related to both physical and mental health.
Interventions
- Other Aerobic Exercises
1. Timing of Exercise: Aerobic exercises were performed on non-dialysis days. This scheduling avoids post-dialysis fatigue and hypotensive effects, optimizing patient safety and performance. 2. Frequency: Patients was engaged in aerobic exercise 3 times per week on non-consecutive days, to allow sufficient recovery time between sessions. 3. Duration of Each Session: * Total Duration: Each exercise session was last between 20 to 45 minutes. * Warm-Up: 5-10 minutes of low-intensity - Other Conventional Program
1\. Breathing Exercises \- Diaphragmatic Breathing: Instruct patients to place one hand on their chest and the other on their abdomen. They should inhale deeply through their nose, allowing the abdomen to rise, and then exhale slowly through their mouth. This breathing technique has been shown to reduce stress, improve respiratory efficiency, and enhance relaxation . For optimal benefits, patients should practice this for 5-10 minutes, 2-3 times a day. Stretching Exercises Hamstring Stretch: I
Primary outcome measures
- Serum Uric Acid [Time frame: from enrollment to the end of 6 weeks of treatment]
Secondary outcome measures (2)
- Change in Functional ability of the patient [Time frame: from enrollment to the end of 6 weeks of treatment]
- Change in Quality of life [Time frame: from enrollment to the end of 6 weeks of treatment]
Eligibility criteria
Inclusion criteria
- Hemodialysis patients aged 40-60years
- Patients are medically stable and able to participate in physical activity.
- Participants are able to understand the commands.
- Participants must be stable on hemodialysis for at least 3 months.
Exclusion criteria
- Patients with significant cardiovascular or respiratory diseases, or other conditions that could impair their ability to exercise.
- Severe cognitive impairment or psychiatric conditions that could interfere with study participation.
- patients with acute medical conditions.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Physical Therapy faculty, Cairo University — Cairo
Identifiers
NCT: NCT07076888 · P.T.REC/025/00123