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Recruiting NCT07069660

Compass 3: A Novel Transition Program to Reduce Disability After Stroke

No phase Interventional Stroke

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: COMPASS, Education Program.
Who it may be relevant to
Registry conditions: Stroke. Basic parameters: from 55 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Compass 3: A Novel Transition Program to Reduce Disability After a Stroke

Overview

This study evaluates a program designed to help individuals transition from inpatient rehabilitation to home following an ischemic or hemorrhagic stroke. Half of the participants will receive a stroke education program while the other half will receive an environmental modifications program.

Detailed description

A gap in care exists at the point of transition from inpatient rehabilitation (IR) to home, when survivors encounter new environmental barriers due to the cognitive and sensorimotor sequelae of stroke. Resolving these barriers and improving independence in the community have potential to significantly improve stroke survivors' long-term morbidity.

Investigators will conduct a randomized, controlled multi-center trial (RCT) and concurrent implementation evaluation and review of process data to examine therapeutic efficacy, cost-effectiveness and implementation potential of a compensatory intervention (COMPASS) designed to improve daily activity performance and participation outcomes in persons transitioning home from inpatient rehabilitation (IR) following a stroke.

Interventions

  • Behavioral COMPASS
    The data from the baseline assessment will be used to develop an environmental modification intervention plan. Environmental modifications will be installed before discharge if possible. Problem areas addressed are participant specific (tailored), but the process to identify and address the target area is systematic. All participants will receive identical intervention components. The standardized components include assessment, identification of problematic activities (and environmental barriers
  • Behavioral Education Program
    The control group will experience the same effects of time and attention in the home but no effect on the outcome of interest.

Primary outcome measures

  • Admission to SNF (skilled nursing facility) [Time frame: From enrollment to 12 months post-discharge from inpatient rehabilitation facility]

Eligibility criteria

Inclusion criteria

  • Aged ≥55 years at the time of screening
  • Acute stroke diagnosis (IS or ICH) verified by the stroke team or medical record
  • Independent in activities of daily living (ADLs) prior to stroke (premorbid Modified Rankin Scale score ≤2)
  • Plan to discharge to home from an IR
  • Capable of giving informed consent which includes compliance with the requirements and duration of participation as listed in the Informed Consent Form (ICF).

Exclusion criteria

  • Life expectancy <6 months
  • Cognitive impairment that the participant's stroke team or a research team member believes impairs their ability to provide informed consent or make reasoned choice including the interpretation of the self-rated scales
  • Any communication problem that would prevent study completion
  • Residence in a congregate living facility
  • Not eligible for a therapeutic pass
  • Residence outside of the designated catchment area (specific catchment distance to be determined by each site)
  • Site investigator's judgment that the participant would not be able to complete research procedures or interventions
  • Participation in another research study that in the site investigator's judgment could interfere or conflict with this research study's assessments or interventions

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

United States · 2 centers
  • University of Missouri — Columbia
  • Washington University in St. Louis — St Louis

Identifiers

NCT: NCT07069660 · 202501232 · 2R01HD092398-06A1

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗