Non-Helium Magnetoencephalography in Autism Spectrum Disorder
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Magnetoencephalography.
- Who it may be relevant to
- Registry conditions: Autism Spectrum Disorder (ASD). Basic parameters: 6 years — 12 years · Male.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Non-Helium Magnetoencephalography for Identifying Neurobiological Features and Functional Biomarkers in Children With Autism Spectrum Disorder: An Observational Cohort Study
Overview
The goal of this observational study is to learn how brain activity in children with autism spectrum disorder (ASD) differs from typical developing children using magnetoencephalography (MEG). The main questions this study aims to answer are: Do children with ASD show different patterns of neural oscillation compared to typically developing children? Can MEG identify specific brain features that help ASD diagnosis? Participants will undergo MEG scan in both resting and tasking state, and their brain activity will be analyzed for characteristic neural oscillations and connectivity patterns. This study may help develop better tools for early ASD diagnosis.
Interventions
- Diagnostic test Magnetoencephalography
Participants will undergo magnetoencephalography scan in both resting and tasking state.
Primary outcome measures
- Identification of Neural Oscillation Characteristics in Children with Autism Spectrum Disorder [Time frame: Baseline assessment (single time point, within 1 week of enrollment).]
Eligibility criteria
Inclusion criteria
- Boys aged 6 to 12 years;
- Diagnosis of Autism Spectrum Disorder meeting DSM-5 criteria;
- Intelligence quotient (IQ) score > 70 (assessed via Wechsler Intelligence Scale for Children or other validated cognitive test);
- Sufficient compliance to participate in MEG experiments.
Exclusion criteria
- Comorbid neurological disorders, genetic syndromes, or severe developmental disabilities;
- Metallic implants that may interfere with MEG signal acquisition;
- Current use of antipsychotic medications or sedatives.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Guangzhou Women and Children's medical center — Guangzhou
Identifiers
NCT: NCT07064967 · 447A01