Sacral Canal Block for Hip Replacement the Efficacy and Safety of Controlled Intraoperative Hypotension
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An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Sacral canal block combined with general anesthesia, Simple general anesthesia.
- Who it may be relevant to
- Registry conditions: Postoperative Pain. Basic parameters: from 45 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Sacral Canal Block for Hip Replacement the Efficacy and Safety of Controlled Intraoperative Hypotension:a Single-center, Prospective, Randomized Controlled Study
Overview
To observe the efficacy and safety of sacral canal block in controlled blood pressure reduction during hip replacement in the elderly, and to provide a better option for controlled blood pressure reduction during clinical hip surgery.
Detailed description
Confirm the effectiveness of sacral canal block in controlled blood pressure reduction during hip replacement surgery in the elderly.
The patient underwent sacral canal block 30 minutes before the operation. The time from the start of the block to achieving the target blood pressure for controlled blood pressure reduction, the duration of the target blood pressure, and the blood pressure variability at different time points were observed. The blood pressure variability was used to evaluate the effect of controlled blood pressure reduction during the operation, the intraoperative blood loss, and the surgeon's satisfaction. It has been confirmed that sacral canal block can effectively achieve the purpose of controlled blood pressure reduction in hip replacement surgery for the elderly.
Clarify the safety of sacral canal block for controlled hypotension in hip replacement surgery.
The patient underwent sacral canal block 30 minutes before the operation. Observe from the start of the block to the regression of the block plane, and the patient was lowered Limb tissue oxygen saturation, peripheral perfusion index, unexpected hypotension, heart rate variability, pulse oxygen saturation, and whether there are complications related to sacral canal block such as local anesthetic poisoning, general spinal anesthesia, regional nerve injury, epidural hematoma, puncture site infection, etc. Meanwhile, the general information of the patients was recorded, including the duration of the operation, the consumption of opioids during the operation, the postoperative pain score, the incidence of nausea and vomiting, and the recovery of sensorimotor sensation in the postoperative block plane regression of the patients, etc. It is clear that sacral canal block can be safely used for controlled blood pressure reduction during hip replacement surgery in the elderly.
Interventions
- Procedure Sacral canal block combined with general anesthesia
Sacral canal block: The patient lies on their side, with the back perpendicular to the edge of the operating table. The knee joints of the lower limbs are flexed, the thighs are close to the abdomen, and the waist is arched backward as much as possible, resembling a "shrimp" shape. The space between the sacrum and coccyx of the patient (sacral hiatus) is fully exposed. By using a low-frequency probe (such as 2-5 MHZ), the strong echo of the sacrum, the low echo of the sacral canal, and the echo - Procedure Simple general anesthesia
General anesthesia: Midazolam (0.2mg/kg), sufentanil (0.2-0.4μg/kg), etomidate (0.15-0.3 mg/kg), and rocuronium (0.6 mg/kg) were induced. After the patient's muscles were completely relaxed, a laryngeal mask was placed. Connect the anesthesia machine and set the ventilator parameters: Vol.Mode, tidal volume 6-8ml/kg, frequency 10-14 times /min, inhalation-exhalation ratio 1:2, and maintain EtCO2 at 35-45mmHg during the operation. Propofol (4-12mg/kg/h) and remifentanil (0.05-2ug/kg/min) were mai
Primary outcome measures
- The onset time for blood pressure to drop from the basal blood pressure to the controlled antihypertensive target value [Time frame: during surgery]
Secondary outcome measures (5)
- Oxygen saturation of the lower extremity tissue on the healthy side（%） [Time frame: during surgery]
- Peripheral perfusion index [Time frame: during surgery]
- heart rate(times/minute) [Time frame: during surgery]
- Intraoperative blood loss（Milliliters） [Time frame: Day 1]
- The cumulative dosage of anesthetic drugs used [Time frame: Day 1]
Eligibility criteria
Inclusion criteria
- Over 45 years old;
- ASA Grade II - III;
- BMI 18-35kg/㎡;
- Agree to participate in this study and sign the informed consent form.
Exclusion criteria
- Those who refuse to participate in the experiment;
- Those who suffer from language or hearing impairments and are unable to communicate;
- Those with contraindications for sacral canal block.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
China · 1 center
- General hospital of Ningxia medical university — Yinchuan
Identifiers
NCT: NCT07064434 · Wenxuan Ma-2025-1