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Not yet recruiting NCT07063953

Effects of Egoscue Exercises in Patients With Knee Osteoarthritis

No phase Interventional Knee Osteoarthritis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Standard Physical Therapy, Egoscue Exercises.
Who it may be relevant to
Registry conditions: Knee Osteoarthritis. Basic parameters: 45 years — 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Pakistan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Effects of Egoscue Exercises on Pain, Range of Motion and Physical Function in Patients With Knee Osteoarthritis

Overview

Knee osteoarthritis (KOA) is a chronic, debilitating illness with multiple etiologies that affects the entire knee joint. It is a leading cause of disability among the elderly population and necessitates effective interventions beyond pharmacotherapy due to the associated risks. This study will address the existing literature gap by focusing on a novel therapeutic approach known as 'Egoscue Exercises', for managing knee osteoarthritis in the affected population.

Detailed description

This Randomized Controlled Trial will be conducted at Riphah Rehab Training and Research Center, Lahore and District Health Quarter Hospital (DHQ), Sahiwal in a time span of 8 months. A sample of 42 participants aged 45-65 years, diagnosed with Grade 02 and 03 Knee Osteoarthritis, will undergo a comprehensive physiotherapy protocol, which includes standard physiotherapy knee OA treatment, either alone or in combination with Egoscue exercises. Participants will receive a minimum of 3 sessions per week, across four weeks.

Randomization, conducted by computer-generated stratified randomization, will ensure unbiased allocation to the two groups. Data collection will be carried out at baseline, 2 weeks, and 4 weeks, and includes outcomes in the form of pain measured by Numeric Pain Rating Scale (NPRS), range of motion measured by Goniometer, and physical function evaluated by Western Ontario and McMaster Universities Arthritis (WOMAC) index. The single-blind study will incorporate rigorous statistical analysis, using IBM SPSS software, version 25 for descriptive statistics, normality, and intergroup differences via t-tests and U tests.

Interventions

  • Other Standard Physical Therapy
    Hot pack \& Transcutaneous Electric Nerve Stimulation (TENS) Myofascial Release Mulligan Mobilization with Movement Exercises
  • Other Egoscue Exercises
    Warm Up Exercises (5 min) which includes Stretching ,Walking (Forward, Backward, Sideways), Arm Circles, Side bends, March on the spot, Knee lifts, Standing Gluteal Contractions , Sitting heel raises, Isolated hip flexor lifts on a towel, Supine groin stretch on towels, Static back, Sitting Knee Pillow Squeezes, Sitting floor, Progressive supine groin, Supine calf-hamstring stretch with a strap,Foot circles and point flexes, Cool Down and Breathing Exercises

Primary outcome measures

  • Range of Motion [Time frame: upto 4 weeks]
  • Western Ontario and McMaster Universities Arthritis (WOMAC) index [Time frame: upto 4 weeks]
  • Numerical Pain Rating Scale (NPRS) [Time frame: upto 4 weeks]

Eligibility criteria

Inclusion criteria

  • Age group between 45 and 65 years ,
  • Both genders male and female ,
  • BMI ˃ 25 , and Knee OA clinically or radiologically diagnosed by Kellgren-Lawrence Method, Grade II and III

Exclusion criteria

  • Age less than 45 years or older than 65 years,
  • BMI < 25, Knee OA in grade I and IV, and
  • Patients on steroid therapy and intra articular injection

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

Pakistan · 1 center
  • Basharat Hospital, Sahiwal — Sahiwal

Publications

  • Sharma L. Osteoarthritis of the Knee. N Engl J Med. 2021 Jan 7;384(1):51-59. doi: 10.1056/NEJMcp1903768. No abstract available. PMID 33406330
  • Cui A, Li H, Wang D, Zhong J, Chen Y, Lu H. Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies. EClinicalMedicine. 2020 Nov 26;29-30:100587. doi: 10.1016/j.eclinm.2020.100587. eCollection 2020 Dec. PMID 34505846
  • Giorgino R, Albano D, Fusco S, Peretti GM, Mangiavini L, Messina C. Knee Osteoarthritis: Epidemiology, Pathogenesis, and Mesenchymal Stem Cells: What Else Is New? An Update. Int J Mol Sci. 2023 Mar 29;24(7):6405. doi: 10.3390/ijms24076405. PMID 37047377
  • Kondal S, Kulkarni V, Gaikwad A, Kharat A, Pant A. Automatic Grading of Knee Osteoarthritis on the Kellgren-Lawrence Scale from Radiographs Using Convolutional Neural Networks [Internet]. arXiv.org. 2020 [cited 2024 Jun 25].
  • Yunus MHM, Nordin A, Kamal H. Pathophysiological Perspective of Osteoarthritis. Medicina (Kaunas). 2020 Nov 16;56(11):614. doi: 10.3390/medicina56110614. PMID 33207632
  • Siddiq MAB, Clegg D, Jansen TL, Rasker JJ. Emerging and New Treatment Options for Knee Osteoarthritis. Curr Rheumatol Rev. 2022;18(1):20-32. doi: 10.2174/1573397117666211116111738. PMID 34784876

Identifiers

NCT: NCT07063953 · REC/RCR &AHS/24/0146 Momina

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗