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Not yet recruiting NCT07046390

TIPS Block vs. IV Analgesia for Postoperative Pain After Knee Arthroscopy

No phase Interventional Knee Arthroscopic Surgery Nerve Block

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: nerve block with bupivacaine 0.25%, No intervention.
Who it may be relevant to
Registry conditions: Knee Arthroscopic Surgery, Nerve Block. Basic parameters: 18 years — 40 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Comparative Study Between Triple Injection Peri-Sartorius (TIPS) Block Versus Intravenous Analgesia for Postoperative Analgesia After Knee Arthroscopy

Overview

In this study participants are aiming to compare triple injection peri-sartorius (TIPS) block versus intravenous analgesia for postoperative analgesia after knee arthroscopy regarding efficacy of pain relief and early ambulation

Detailed description

Arthroscopic knee surgery is a commonly performed orthopedic procedure due to being minimally invasive and providing early recovery. A significant number of patients have severe postoperative pain despite using small incisions leading to poor quality of postoperative recovery. Currently, multimodal analgesia is a widely used method of pain relief and also to improve patient functionality and satisfaction scores. Systemic opioids and non-steroidal anti-inflammatory drugs (NSAIDs) have been the mainstay for treating postoperative pain after knee surgery. The traditional high-dose opioid approach is associated with increased opioid-related side effects eg: (Nausea ,vomiting and delayed recovery ).NSAIDs are effective as part of a multimodal analgesic approach, but their use can be limited due to concerns regarding coagulopathy or impairment of renal function and GIT side effects.Ultrasound guidance in regional anaesthesia is increasingly being used leading to approaches to the sciatic nerve block, femoral nerve block (FNB), adductor canal block (ACB) and obturator nerve block increasingly motivated as an element of multimodal analgesia regimen in many operations, including knee arthroscopy.Sub sartorial block has been studied for its efficacy in providing analgesia following knee surgeries while preserving quadriceps muscle power. However, misnomers have been prescribed at different locations for different block approaches. TIPS block targets motor-sparing analgesia through injection at three planes ultrsound guided.Study Procedures: Patients will be enrolled in this randomly allocated using computer-based randomization into two groups with (26) patients in each group

* Group 1 (study group number 1) will receive triple injection peri-sartorius (TIPS) block. The block will be done after induction of general anesthesia before skin incision * Group 2 (study group number 2) (control group )will receive conventional analgesic regimen without having a regional block.

Interventions

  • Drug nerve block with bupivacaine 0.25%
    0.25% bupivacaine
  • Drug No intervention
    No intervention

Primary outcome measures

  • postoperative analgesics [Time frame: 24 hours postoperative]
Secondary outcome measures (1)
  • The secondary outcomes will be the total morphine consumption in mg , ambulation distances during the first 24 hours postoperative in meters [Time frame: 24 hours postoperative]

Eligibility criteria

Inclusion criteria

.Age 18-40 years undergoing knee arthroscopy. .Sex: Both sexes.

.American Society of Anaesthesiologists (ASA) Physical Status Class I and II

Exclusion criteria

.Declining to give written informed consent. .History of allergy to the medications used in the study. .Contraindications to regional anesthesia (including patient refusal, coagulopathy and local infection).

Psychiatric disorder. .American Society of Anesthesiologists (ASA) Physical Status Class III and IV.

  • Patients with body mass index (BMI) >35 kg/m2 .Neurological deficits or mobility-related disorders of the non-operated limb .
  • Moderate to severe hepatic , renal diseases and cardiac disease.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Prevention

Study locations

Egypt · 1 center
  • Ain Shams University — Cairo

Identifiers

NCT: NCT07046390 · FMASU MD24/2024

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗