Recruiting NCT07045870
Methods of Post Operative Analgesia in Patients Undergoing Thyroidectomy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: group L : will receive lidocaine, group k : will receive Ketamine, group c: will recieve .9% saline.
- Who it may be relevant to
- Registry conditions: Thyroid Disorder. Basic parameters: 18 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effects of Perioperative Intravenous Lidocaine Infusion Versus Ketamine Infusion For Postoperative Analgesia in Patients Undergoing Thyroidectomy : A Randomized Controlled Trial
Overview
this study aims to compare between effects of lidocaine and ketamine infusion on postoperative analgesia in patients undergoing thyroidectomy.
Interventions
- Drug group L : will receive lidocaine
group L : will receive 1.5 mg/kg bolus of iv lidocaine 10 minutes before anaesthesia induction then continuous iv infusion rate 1.5 mg / kg / h - Drug group k : will receive Ketamine
patients will receive .25 mg / kg bolus of iv ketamine 10 minutes before anaesthesia induction then continuous iv infusion of ketamine at .25 mg /kg /h - Drug group c: will recieve .9% saline
group c will be injected with equivalent volumes and rates of .9% saline using the same application scheme as the lidocaine and ketamine as a control group
Primary outcome measures
- the effect of perioperative intravenous lidocaine and ketamine infusion for postoperative analgesia in patients undergoing thyroidectomy [Time frame: 24 hours posftoperative]
Eligibility criteria
Inclusion criteria
- age from 18 to 75 years old
- both sexes
- scheduled for thyroidectomy
Exclusion criteria
- toxic goiter
- (BMI) exceeding 30 kg / m2
- un controlled hypertension
- sever liver or kidney disorders
- allergy to study drugs
- hyperthyroidism
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Other
Study locations
Egypt · 1 center
- Sohag university hospital — Sohag
Publications
- Ludwig B, Ludwig M, Dziekiewicz A, Mikula A, Cisek J, Biernat S, Kaliszewski K. Modern Surgical Techniques of Thyroidectomy and Advances in the Prevention and Treatment of Perioperative Complications. Cancers (Basel). 2023 May 26;15(11):2931. doi: 10.3390/cancers15112931. PMID 37296896
- Javidi S, Sadrizadeh S, Sadrizadeh A, Bonakdaran S, Jarahi L. Postoperative complications and long-term outcomes after total and subtotal thyroidectomy: a retrospective study. Sci Rep. 2025 Jan 29;15(1):3705. doi: 10.1038/s41598-024-79860-8. PMID 39881145
- Jain SN, Lamture Y, Krishna M. Enhanced Recovery After Surgery: Exploring the Advances and Strategies. Cureus. 2023 Oct 17;15(10):e47237. doi: 10.7759/cureus.47237. eCollection 2023 Oct. PMID 38022245
Identifiers
NCT: NCT07045870 · Soh-Med--25-6-11MS