Aerobic Versus Resistive Intradialytic Training Effect on Atherogeinc Index in Hemodialysis Patients

Overview

the goal of the clinical trial is to study the effect of aerobic and resistive exercises on atherogenic index in hemodialysis patients the study will include three groups of both sex the first group will participate in aerobic exercise ,the second group will participate in resistive exercise and the third group will be control group

Detailed description

This study will be carried out on sixty male and female patients. They will be recruited from National Institute of Kidney and Urology, Mataria,Their ages will be ranged from (40-60) years old these patients will be assigned into three groups (A, B and C). The design of this study will be a randomized controlled trail (RCT).The patients will be informed about the study procedure and signed the informed consent prepared for this study . The study will follow the instructions of ethical committee of faculty of physical therapy, Cairo University. Inclusive criteria

1. Maintenance hemodialysis ≥ 3 months. 2. BMI will be ranged from 18.5 to 29.9 kg/m². 3. Age ≥ 40years and ≤ 60 years. 4. Hemodialysis 3 times a week.

Exclusive criteria:

1. patients suffered from any central and peripheral nervous system diseases. 2. patients suffered from serious complications, such as heart failure, severe infection and malignant tumor. 3. uncontrolled hypertension with systolic blood pressure ⩾200 mm Hg and/or diastolic blood pressure ⩾120 mm Hg, 4. unstable angina

Interventions

• Other Aerobic exercise without medication
  twenty patients will participate in moderate intensity intradialytic aerobic training for 12 weeks. (3 times per week). Using Horizontal electromagnetically braked cycle ergometer during the first half of the dialysis session. (1) Frequency: received intradialytic, lower-limb, cycling exercise three times per week on alternative days (2) Intensity: the intensity of exercise will be at 12-14 (moderate-intensity: somewhat hard or reports of feeling a little bit tired but still ok to continue) bas
• Other resistive exercise without medication
  Twenty patients will participate in moderate intensity intradialytic resistive training for 12 weeks. (3 sessions per week) using ankle weights. During session: The warming up phase for 5-minute in form of circulatory exercises, then the main exercise phase and then cooling down phase for 5 minutes. in form of circulatory exercises. The training protocol consisted of five lower-body resistance exercises using ankle weights 3 days/week, The intensity of the program will be moderate, starting wi
• Other circulatory exercise without medication
  this group will include 20 patients will participate in circulatory exercises and will be evaluated at the beginning and at the end of the study.

Primary outcome measures

• atherogenic index [Time frame: three months]

Eligibility criteria

Inclusion criteria

.Maintenance hemodialysis ≥ 3 months. .BMI will be ranged from 18.5 to 29.9 kg/m². .Age ≥ 40years and ≤ 60 years. .Hemodialysis 3 times a week.

Exclusion criteria

.patients suffered from any central and peripheral nervous system diseases. .patients suffered from serious complications, such as heart failure, severe infection and malignant tumor.

.uncontrolled hypertension with systolic blood pressure ⩾200 mm Hg and/or diastolic blood pressure ⩾120 mm Hg.

.unstable angina

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation

Randomized

Model

Parallel assignment

Masking

Single blind

Primary purpose

Treatment

Study locations

Egypt · 2 centers

• National Institute of Kidney and Urology, Mataria — Cairo
• National Institute of Kidney and Urology, Mataria — Cairo

Identifiers

NCT: NCT07045064 · exerciseinhemodialysispatients

Primary sources (government registries)

• ClinicalTrials.gov (US NIH)

View this study on ClinicalTrials.gov ↗