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Not yet recruiting NCT07044986

Ultrasonographic Evaluation of the Ulnar Nerve in Individuals With and Without Generalized Joint Hypermobility

Observational Hypermobility, Joint

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: no intervention.
Who it may be relevant to
Registry conditions: Hypermobility, Joint. Basic parameters: 18 years — 40 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

This study will include 30 individuals diagnosed with Generalized Joint Hypermobility (GJH) based on the Beighton score and 30 healthy controls without GJH. Participants will undergo Tinel's test and the flexion-compression test. The presence of ulnar nerve-related symptoms such as pain and numbness will be recorded. Ultrasonographic evaluation of the ulnar nerve will be performed at the level of the medial epicondyle, as well as 2 cm proximal and distal to it. Cross-sectional area and diameter of the ulnar nerve will be measured at each site, repeated three times, and the average will be used. Additionally, ulnar nerve mobility during elbow flexion and extension will be assessed. The nerve will be classified as stable if it remains within the cubital tunnel, subluxated if it moves to the level of the epicondyle, and dislocated if it shifts anterior to the medial epicondyle.

Interventions

  • Other no intervention
    no intervention

Primary outcome measures

  • Ulnar nerve cross-sectional area (CSA) at the medial epicondyle [Time frame: 0 day]
  • Ulnar nerve cross-sectional area (CSA) at the 2 cm proximal of medial epicondyle [Time frame: 0 day]
  • Ulnar nerve cross-sectional area (CSA) at the 2 cm distal of medial epicondyle [Time frame: 0 day]
  • Ulnar nerve diameter [Time frame: 0 day]
  • Ulnar nerve mobility classification during elbow flexion (stable/subluxated/dislocated) [Time frame: 0 day]
Secondary outcome measures (1)
  • Presence of ulnar nerve-related symptoms: [Time frame: 0 day]

Eligibility criteria

Inclusion criteria

  • Aged between 18 and 40 years
  • A Beighton score of 4 or higher (indicative of Generalized Joint Hypermobility)
  • Willingness to participate in the study

Exclusion criteria

  • Being under 18 or over 40 years of age
  • History of surgery or fracture in the elbow region
  • Presence of active infection at the measurement site
  • Presence of congenital anomaly in the upper extremity
  • History of surgery involving neural structures in the upper extremity
  • Presence of malignancy
  • Pregnancy
  • Presence of cognitive or psychiatric disorders

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Case-control

Study locations

Turkey (Türkiye) · 1 center
  • Beylikdüzü State Hospital — Istanbul

Identifiers

NCT: NCT07044986 · BeylikduzuStateH21

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗