Low-Flow Anesthesia and Open-Heart Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Low-flow Anesthesia, Hemodynamics, Open-heart Surgery. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
The Effect of Low-Flow Anesthesia on Hemodynamics in Open-Heart Surgery
Overview
Low-flow anesthesia (LFA) is a technique in which at least 50% of the exhaled air, after carbon dioxide absorption, is mixed with a certain amount of fresh gas and returned to the patient during the next inspiration. In 1974, R. Virtue defined minimal flow anesthesia (MFA) as 0.5 L/min. In 1984, Baker and Simionescu classified LFA as 0.5-1 L/min and MFA as 0.25-0.5 L/min. The aim of this study is to investigate whether there are hemodynamic differences between open-heart surgery cases performed with LFA at different fresh gas flow rates.
Primary outcome measures
- physiological parameter ; heart rate [Time frame: Intraoperatively]
- physiological parameter; systolic/diastolic blood pressure [Time frame: Intraoperatively]
- physiological parameter; SpO2 [Time frame: Intraoperatively]
- Monitoring parameter; Bispectral Index (BIS) [Time frame: Intraoperatively]
- Monitoring parameter; Minimum alveolar concentration (MAC) [Time frame: Intraoperatively]
Secondary outcome measures (3)
- Preoperative data; ASA (American Society of Anesthesiologists) classification [Time frame: 24 hours before surgery]
- Preoperative data [Time frame: 24 hours before surgery]
- Preoperaitive data [Time frame: 24 hours before surgery]
Eligibility criteria
Inclusion criteria
-≥18 years and scheduled for open-heart surgery patients
-ASA I-II-III-IV physical class
Exclusion criteria
- Emergency cases
- Patients under 18 years of age
- Patients who have had open heart surgery before
- Patients for whom the use of inhaled anesthetic agents is contraindicated
- Patients who do not sign a voluntary consent form
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Turkey (Türkiye) · 1 center
- Gazi University Faculty of Medicine — Ankara
Identifiers
NCT: NCT07040735 · 2025-146