Immune-Nutritional Scores and Sleep Quality After Total Abdominal Hysterectomy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Immune-Nutritional Scoring and Postoperative Sleep Assessment.
- Who it may be relevant to
- Registry conditions: Immune-Nutritional Indexes (PNI, HALP), Postoperative Sleep Quality. Basic parameters: 18 years — 70 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
A Clinical Evaluation of the Relationship Between Preoperative Immune-Nutritional Scores and Postoperative Sleep Quality in Women Undergoing Total Abdominal Hysterectomy
Overview
This prospective observational study aims to evaluate the relationship between preoperative immune-nutritional status and postoperative sleep quality in women undergoing total abdominal hysterectomy under general anesthesia. Immune-nutritional scores, including the Prognostic Nutritional Index (PNI) and Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) score, will be calculated using routine preoperative blood parameters. Postoperative sleep quality will be assessed using the Richards-Campbell Sleep Questionnaire (RCSQ). Secondary outcomes include postoperative pain scores and patient satisfaction. The study will enroll 60 patients and seeks to determine whether preoperative physiological markers can predict subjective recovery parameters such as sleep and comfort, potentially contributing to personalized perioperative care.
Interventions
- Other Immune-Nutritional Scoring and Postoperative Sleep Assessment
Routine preoperative laboratory data (hemoglobin, albumin, lymphocyte, platelet) will be used to calculate immune-nutritional scores (HALP, PNI). Postoperative sleep quality will be assessed with the Richards-Campbell Sleep Questionnaire (RCSQ).
Primary outcome measures
- Postoperative Sleep Quality Score [Time frame: Postoperative first night]
Secondary outcome measures (2)
- Postoperative Pain Score [Time frame: Post-anesthesia care unit (PACU), postoperative day 1 and day 2 (rest and mobilization)]
- Patient Satisfaction Score [Time frame: Postoperative day 2]
Eligibility criteria
Inclusion criteria
- Female patients aged 18-70
- ASA physical status I-III
- Undergoing elective total abdominal hysterectomy under general anesthesia
- Available complete blood count and biochemistry results within 24 hours preoperatively
- Planned to stay at least one night postoperatively
- Sufficient cognitive ability to understand and complete questionnaires
- Provided written informed consent
Exclusion criteria
- History of neurological or psychiatric illness
- Diagnosed sleep disorders
- Current use of sedative or hypnotic medications
- Undergoing additional surgical procedures during operation
- Requiring postoperative intensive care
- Operated under spinal or epidural anesthesia
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Li J, Guo Q, Ye X, Lin J, Yi C, Mao H, Yang X, Yu X. Prevalence and risk factors of sleep disturbance in continuous ambulatory peritoneal dialysis patients in Guangzhou, southern China. Int Urol Nephrol. 2012 Jun;44(3):929-36. doi: 10.1007/s11255-011-0060-5. Epub 2011 Sep 30. PMID 21960370
- Ishiguro T, Aoyama T, Ju M, Kazama K, Fukuda M, Kanai H, Sawazaki S, Tamagawa H, Tamagawa A, Cho H, Hara K, Numata M, Hashimoto I, Maezawa Y, Segami K, Oshima T, Saito A, Yukawa N, Rino Y. Prognostic Nutritional Index as a Predictor of Prognosis in Postoperative Patients With Gastric Cancer. In Vivo. 2023 May-Jun;37(3):1290-1296. doi: 10.21873/invivo.13207. PMID 37103068
- Farag CM, Antar R, Akosman S, Ng M, Whalen MJ. What is hemoglobin, albumin, lymphocyte, platelet (HALP) score? A comprehensive literature review of HALP's prognostic ability in different cancer types. Oncotarget. 2023 Feb 25;14:153-172. doi: 10.18632/oncotarget.28367. PMID 36848404
- Para E, Uslu N. Cerrahi hastalarında ameliyat sonrası uyku kalitesi ve uyku düzenini etkileyen etmenler. CBU Sağlık Bilimleri Dergisi. 2022;9(3):443-450. doi:10.34087/cbusbed.1034063.
Identifiers
NCT: NCT07038564 · TAH PNI HALP