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Recruiting NCT07034157

A Real-World Study on Ultrasound-Based Screening and Integrated Therapeutic Strategies for Patients With Concomitant Coronary and Cervicocephalic Artery Stenosis

— Observational Coronary Artery Disease Carotid Artery Stenosis Cerebrovascular Disorders

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Percutaneous Coronary Intervention, Cerebrovascular Intervention (CAS ）, No Intervention / Observation.
Who it may be relevant to
Registry conditions: Coronary Artery Disease, Carotid Artery Stenosis, Cerebrovascular Disorders. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

This prospective observational cohort study aims to investigate the prevalence and clinical significance of head and neck arterial stenosis in patients with coronary artery disease (CAD) undergoing or scheduled for percutaneous coronary intervention (PCI). Using Doppler ultrasound as the primary screening tool, the study will assess the degree of stenosis and evaluate the impact of different combined treatment strategies on patient outcomes. The research will provide real-world evidence to optimize integrated care approaches for patients with comorbid cardiovascular and cerebrovascular diseases.

Interventions

  • Procedure Percutaneous Coronary Intervention
    Coronary stenting performed as part of routine care for patients with coronary artery stenosis.
  • Procedure Cerebrovascular Intervention (CAS ）
    Patients with intervention-indicated head and neck artery stenosis will receive carotid artery stenting based on clinical evaluation.
  • Other No Intervention / Observation
    Clinical observation or standard follow-up in patients without significant disease

Primary outcome measures

  • Prevalence of Head and Neck Artery Stenosis in Patients with Coronary Artery Disease [Time frame: At baseline (prior to or during initial hospitalization)]
Secondary outcome measures (7)
  • mRS score [Time frame: 7±1 days or the day discharged]
  • mRS Score [Time frame: 90±7 days]
  • mRS Score [Time frame: 365±30 days]
  • Rate of cardiovascular and cerebrovascular events [Time frame: 90±7 days]
  • Rate of cardiovascular and cerebrovascular events [Time frame: 365±30 days]
  • Short-term complications [Time frame: 90±7 days]
  • Long-term complications [Time frame: 365±30 days]

Eligibility criteria

Inclusion criteria

  • Age ≥18 years;
  • Patients with coronary artery disease scheduled to undergo elective percutaneous coronary intervention (PCI) on the following day.

Exclusion criteria

  • The expected survival is less than 1 years;
  • Simultaneously merge other serious diseases;

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

China · 1 center
  • Beijing Anzhen Hospital — Beijing

Identifiers

NCT: NCT07034157 · KS2025006

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗