Diagnosis of Wire Syndrome
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Non intervention.
- Who it may be relevant to
- Registry conditions: Orthodontic Wires. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
How to Diagnose Wire Syndrome ? A Classification Based on Retrospective Studies and Clinical Experience
Overview
The Wire Syndrome (WS) refers to aberrant, unexpected, unexplained, or excessive dental movements involving teeth held by an intact post-orthodontic retention wire. Its prevalence ranging from 1.1% to 43%. It is a chronic, progressive pathological process, generally asymptomatic, resulting in a new malocclusion that is not due to relapse or a physiological process, and whose aesthetic and/or functional dento-periodontal consequences are harmful. The causes are multifactorial origin. In the early stages of Wire Syndrome, dental and periodontal consequences are minors. These issues are thought to progressively worsen over time.However, to date, no author has proposed an appropriate diagnostic approach. Indeed, several diagnostic criteria have been reported in the literature, but their hierarchical ranking, in terms of importance and specificity, has yet to be determined. The main objective of this study is therefore to propose a classification of WS according to its severity, based on a shared framework between periodontists and orthodontists. This classification should, facilitate early detection of the syndrome, and reduce diagnostic delays and therapeutic errors. It should also help clarify prognosis and improve interprofessional collaboration in developing personalized treatment plans.
Interventions
- Other Non intervention
Non intervention
Primary outcome measures
- Presence of Wire Syndrome [Time frame: At the inclusion]
- severity classification of Wire Syndrome [Time frame: At the inclusion]
Secondary outcome measures (2)
- Major clinical diagnosis criteria (Fleiss Kappa) [Time frame: At the inclusion]
- Minor clinical diagnostis criteria (Fleiss Kappa) [Time frame: At the inclusion]
Eligibility criteria
Inclusion criteria
- Presence of fixed orthodontic retention (maxillary and/or mandible)
- Comprehensive documentation available
- Systemically healthy
- Presence or not of a Wire Syndrome
Exclusion criteria
- Patient with other orthodontic retention.
- Patient unable to understand french
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
France · 1 center
- CHU NICE — Nice
Publications
- Dridi SM, Aroca S, Antonarakis GS, Fontas E, Masucci C, Reners M, Roussarie F, de Sanctis M, Charavet C. Diagnosis of wire syndrome: A severity-based classification developed by a Multidisciplinary Working Group. Int Orthod. 2026 Jul 7;24(4):101207. doi: 10.1016/j.ortho.2026.101207. Online ahead of print. PMID 42413243
Identifiers
NCT: NCT07030023 · 25Ondonto03