Oral Health Condition Among a Group of Ionizing Radiation Field Workers
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Salivary redox biomarkers.
- Who it may be relevant to
- Registry conditions: Salivary Redox Biomarkers and Oral Health. Basic parameters: 30 years — 40 years · Male.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Salivary Redox Biomarkers in Relation to Oral Health Condition Among a Group of Ionizing Radiation Field Workers
Overview
The goal of this study is to test the effect of ionizing radiation on salivary Redox status among a group of ionizing radiation workers by measuring salivary biomarkers(malondialdehyde,8\_hydroxy\_deoxyguanosine and catalase) and measuring oral health condition by plaque index. 90 male subjects will be enrolled in this study between 30\_40 years old worked in Baghdad teaching hospital ,30 subjects exposed from computed tomography department ,30 subjects exposed from x\_ray department and 30 subjects unexposed from laboratory department in the same hospitals. The method of the study is taking unstimulated saliva sample from the subjects and oral health measure.
Interventions
- Radiation Salivary redox biomarkers
Salivary redox biomarkers
Primary outcome measures
- oral health status [Time frame: Baseline: the subjects must be fasting. up to two hours saliva collection]
Secondary outcome measures (3)
- Salivary Malondialdehyde biomarker [Time frame: Baseline:saliva collection for malondialdehyde . up to two hours fasting for all subjects.]
- Salivary 8_ hydroxy_deoxyguanosine biomarker [Time frame: Baseline:saliva collection for 8_hydroxy_deoxyguanosine .up to two hours fasting for all subjects.]
- Salivary catalase biomarker [Time frame: Baseline:saliva collection for catalase . up to two hours fasting for all subjects.]
Eligibility criteria
Inclusion criteria
- male, 30\_40 years ,no history of systemic disease, no medical treatment taken at least 3 months before sampling and the subjects are exposed to radiation 5\_ 10 years
Exclusion criteria
- subjects with medical history , subjects are taken medications during last 3 months , the subjects are exposed to radiation less than 5 years or more than 10 years
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-crossover
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07020078 · MustansiriyahU