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Recruiting NCT07016685

Prognosis of Veno-Venous Extracorporeal Membrane Oxygenation in Emergency Thoracic Surgery

Observational VV-ECMO Thoracic Surgery Emergency Surgery ARDS

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: VV-ECMO, Thoracic Surgery, Emergency Surgery, ARDS. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Prognostic Factors for 90-day Mortality in Patients Undergoing Veno-venous Extracorporeal Membrane Oxygenation for Emergency Thoracic Surgery

Overview

Veno-vneous extracorporeal membrane oxygenation (VV-ECMO) is an established support strategy for acute respiratory failure, but its role in the perioperative management of emergency thoracic surgery remains poorly defined. This retrospective, multicenter, observational study aims to assess the clinical outcomes and prognostic factors in this high-risk population. Patients undergoing emergency thoracic procedures requiring VV-ECMO will be compared to a control cohort of patients treated with VV-ECMO for medical respiratory failure. Data will be collected from two French academic centers (CHU Amiens-Picardie and CHU Dijon).

Primary outcome measures

  • 90-day all-cause mortality [Time frame: 90 days]
Secondary outcome measures (2)
  • 90-day mortality in oncologic vs. non-oncologic thoracic surgery [Time frame: 90 days]
  • Postoperative complication rates [Time frame: 90 days]

Eligibility criteria

Inclusion criteria

  • Adults ≥ 18 years
  • VV-ECMO initiated during or after emergency thoracic surgery
  • No opposition to data use

Exclusion criteria

  • Pregnant women
  • Veno-Arterial ECMO patients
  • Patients under legal protection

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Case-only

Study locations

France · 1 center
  • CHRU Amiens — Amiens

Publications

  • Beyls C, Soulier-Zaninka Q, Georges O, Nguyen M, Dheilly T, Nicolas M, Huette P, De Dominicis F, Abou-Arab O, Guinot PG, Mahjoub Y. Perioperative Veno-Venous Extracorporeal Membrane Oxygenation in Non-Elective Thoracic Surgery: A Propensity-Matched Bicentric Comparison With Medical Indication. Interdiscip Cardiovasc Thorac Surg. 2025 Nov 6;40(11):ivaf255. doi: 10.1093/icvts/ivaf255. PMID 41134639

Identifiers

NCT: NCT07016685 · PI2025_843_0071

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗