Monitoring Arm Recovery After Stroke (MARS)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Biomechanical analysis of arm movement, Pose estimation of arm movement.
- Who it may be relevant to
- Registry conditions: Stroke. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United Kingdom
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Developing an Accessible, Cost-Effective Motion Analysis Tool for Arm Movement After Stroke
Overview
People who have a stroke often find it hard to do the things they did before. This can be caused by problems with arm movement. One in five people do not get any arm movement back after a stroke. Arm movements can be measured accurately in a laboratory, but it is very expensive and not easy to do in hospital. That means it is hard to tell if the arm is recovering to move like it did before the stroke or adapting to perform tasks in other ways. To tell if a treatment is working, the investigators are making a phone app to record arm movement, using the camera. The recordings will be turned into data showing movement difficulties and sent to hospital records for clinicians. Clinicians will see if movement changes, to help choose the best treatment. The investigators are looking for twelve stroke survivors to help test this app. * The session will be at King's College London, on Guy's Campus. * It will run for 2-3 hours. * Participants will wear a vest or tight-fitting clothes. * The investigators will place non-invasive markers on the participants arm. * The investigators will video simple movements such as drinking from a cup. * The investigators will also measure the same simple movements using the laboratory cameras. This will show us if our app can measure arm movement as well as laboratory tests. If they do, the investigators will know the app is accurate. In future this technology can improve recovery by correcting stroke survivors when they perform home exercises.
Detailed description
Upper limb recovery after stroke remains poor and 20% of stroke survivors do not recover arm movement. To improve outcome and advance insights to recovery mechanisms, an international collaboration has proposed a standardised set of outcome measures, including movement kinematics. Kinematics are moresensitive to change than clinical measures and can differentiate whether recovery is achieved by compensating to impairment or true recovery. However, kinematic assessments are not performed in clinical practice as 3-D motion capture requires expensive equipment and expertise for set-up and analysis.
The investigators therefore aim to develop a low-cost tool to measure kinematics. Open-source Artificial Intelligence models can detect positions and orientations on video and are called pose estimation models. The objectives will be to deploy and test these models in stroke survivors. The investigators will invite 12 stroke survivors with mild to moderate upper limb impairment and compare the accuracy of the models to gold-standard kinematic analysis when performing a variety of upper limb tasks. The investigators will optimise the models in case of any discrepancies. The investigators will develop a front-end smartphone app to instruct, record and provide feedback of arm movement performance to clinicians and stroke survivors. The investigators will develop the software back-end performing analysis of recorded movements and integrating these findings into electronic healthcare records for longitudinal performance tracking.
This accessible technology will provide clinicians kinematic analyses. Kinematics can guide treatment modifications and progression to improve upper limb movement.
Interventions
- Behavioral Biomechanical analysis of arm movement
Marker based kinematic analysis - Behavioral Pose estimation of arm movement
Marker free kinematic analysis
Primary outcome measures
- Pose estimation model accuracy [Time frame: During intervention]
Secondary outcome measures (5)
- Fugl-Meyer Upper limb Assessment [Time frame: baseline, before intervention]
- Motricity Index [Time frame: baseline, before intervention]
- Cancellation OCS [Time frame: baseline, before intervention]
- Box and block [Time frame: during the intervention]
- ARAT-2 [Time frame: during the intervention]
Eligibility criteria
Stroke survivors
Inclusion criteria
- History of stroke
- Arm impairment evidenced by Fugl-Meyer Upper Limb Assessment between 9-60/66.
Exclusion criteria
- Severe cognitive impairment preventing ability to consent to treatment and understand and follow research protocol
- Severe language deficit preventing ability to consent to treatment and understand and follow research protocol
- Shoulder pain >3/10 on visual analog scale
- Unable to maintain independent sitting balance without a high back support.
- Wheelchair users that are unable to transfer with assistance of 1 to lab chair or whose wheelchair backrest cannot colapse.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
United Kingdom · 1 center
- Centre for Human and Applied Physiological Sciences — London
Identifiers
NCT: NCT07016295 · LRS/RGO-24/25-47508