Recruiting NCT07014111
Fight Fatigue: A Progressive Muscle Relaxation and Walking Intervention to Reduce Fatigue in Adults With ESKD
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Fight Fatigue, Attention Control.
- Who it may be relevant to
- Registry conditions: End Stage Renal Disease on Dialysis. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
Fight Fatigue is evaluating the feasibility and acceptability of a combined progressive muscle relaxation and walking intervention to reduce fatigue for adults with end-stage kidney disease receiving in-center hemodialysis.
Interventions
- Behavioral Fight Fatigue
Combined progressive muscle relaxation and walking (increasing step count) 12-week intervention that consists of education/training followed by text messages. - Other Attention Control
End-stage kidney disease education
Primary outcome measures
- Feasibility of recruitment [Time frame: Baseline to week 12]
- Feasibility of retention [Time frame: Baseline to week 12]
- Acceptability [Time frame: End of study (Week 12)]
- Adherence to the study protocol [Time frame: Baseline to week 12]
Eligibility criteria
Inclusion criteria
- Diagnosis of ESKD diagnosis and receiving hemodialysis for at least 3 months
- Can read and speak English
- Fatigue measured via visual analogue scale, score ≥4 over the last week
- Able to stand and walk one block
- Has a cell phone that can receive text messages
Exclusion criteria
- Patient's nephrologist refuses for them to participate
- Unstable angina
- Unstable pulmonary disease or pulmonary symptoms that preclude participation
- Lower-extremity amputation without prosthetic (BKA, AKA) -Orthopedic or neurologic condition that would preclude walking or tensing/releasing of muscles-
- Cognitive impairment that, in the judgement of the research team, precludes trial participation
- Participation in the formative phase of the development of Fight Fatigue
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Other
Study locations
United States · 1 center
- UI Health/University of Illinois Chicago — Chicago
Publications
- Hannan MF, Fischer MJ, deMartelly V, Lif N, Tintle N, Doorenbos AZ. A combined progressive muscle relaxation and walking intervention for adults with end-stage kidney disease receiving hemodialysis (Fight Fatigue): Study development and protocol. Contemp Clin Trials Commun. 2026 Mar 24;51:101631. doi: 10.1016/j.conctc.2026.101631. eCollection 2026 Jun. PMID 41952779
Identifiers
NCT: NCT07014111 · STUDY2025-0281 · R34AT012770