Enrolling by invitation NCT07002775
Which Position Is Better For CPR In OHCA Patients?
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Transesophageal ultrasound.
- Who it may be relevant to
- Registry conditions: Cardiac Arrest (CA). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Taiwan
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Use Transesophageal Echocardiography Comparing Head Up And Supine Cardiopulmonary Resuscitation On Cerebral And Systemic Hemodynamics In OHCA Patients
Overview
Use Transesophageal ultrasound in OHCA patients to identify the proper CPR position
Interventions
- Device Transesophageal ultrasound
Transesophageal ultrasound with built-in ultrasound software (Philips QLAB 3D quantification advance, Philips Healthcare, USA, speckle tracking echocardiography (STE,Speckle tracking echocardiography) to evaluate stroke volume and cardiac output in different position with the same person
Primary outcome measures
- cardiac output [Time frame: check cardiac output while CPR(Periprocedural)(after TEE insertion) in head up and supine position]
- stroke volume [Time frame: check stroke volume while CPR(Periprocedural)(after TEE insertion) in head up and supine position]
Eligibility criteria
Inclusion criteria
- Out of hospital cardiac arrest patients
Exclusion criteria
- DNR was signed,
- Age under 18
- Trauma patients
- Patients hard to establish advanced airway
- C spine injury patients
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Taiwan · 2 centers
- Chang Bing Show Chawan Memorial Hospital — Changhua
- National Taiwan University Hospital — Taipei
Publications
- Moore JC, Salverda B, Lick M, Rojas-Salvador C, Segal N, Debaty G, Lurie KG. Controlled progressive elevation rather than an optimal angle maximizes cerebral perfusion pressure during head up CPR in a swine model of cardiac arrest. Resuscitation. 2020 May;150:23-28. doi: 10.1016/j.resuscitation.2020.02.023. Epub 2020 Feb 27. PMID 32114071
- Moore JC, Holley J, Segal N, Lick MC, Labarere J, Frascone RJ, Dodd KW, Robinson AE, Lick C, Klein L, Ashton A, McArthur A, Tsangaris A, Makaretz A, Makaretz M, Debaty G, Pepe PE, Lurie KG. Consistent head up cardiopulmonary resuscitation haemodynamics are observed across porcine and human cadaver translational models. Resuscitation. 2018 Nov;132:133-139. doi: 10.1016/j.resuscitation.2018.04.009. PMID 29702188
- Kim T, Shin SD, Song KJ, Park YJ, Ryu HH, Debaty G, Lurie K, Hong KJ. The effect of resuscitation position on cerebral and coronary perfusion pressure during mechanical cardiopulmonary resuscitation in porcine cardiac arrest model. Resuscitation. 2017 Apr;113:101-107. doi: 10.1016/j.resuscitation.2017.02.008. Epub 2017 Feb 16. PMID 28215591
- Debaty G, Shin SD, Metzger A, Kim T, Ryu HH, Rees J, McKnite S, Matsuura T, Lick M, Yannopoulos D, Lurie K. Tilting for perfusion: head-up position during cardiopulmonary resuscitation improves brain flow in a porcine model of cardiac arrest. Resuscitation. 2015 Feb;87:38-43. doi: 10.1016/j.resuscitation.2014.11.019. Epub 2014 Nov 28. PMID 25447353
Identifiers
NCT: NCT07002775 · 202410141RINA