Lower Limb ExoNET: Development and Evaluation for Gait Assistance With Stroke Survivors
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Assist, Resist, Slack.
- Who it may be relevant to
- Registry conditions: Healthy. Basic parameters: 18 years — 70 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
Stroke-related gait impairments, such as poor limb coordination, imbalance, and reduced push-off strength, are often addressed using robotic systems or electrical stimulation, which can be costly, invasive, or insufficient for long-term recovery. Current devices often assist movement but fail to promote functional motor learning. Research supports rehabilitation strategies that amplify gait errors to drive neuroplasticity and adaptation. The LegExoNET (Exoskeletal Network for Elastic Torque) is a novel, passive wearable exoskeleton designed to address this need by enabling both assistive and therapeutic gait training. It stores and releases elastic energy to aid movement while allowing natural joint motion. The system aims to support individuals post-stroke transitioning to independent rehabilitation by offering a lightweight, affordable, and adaptive solution. Initial testing will focus on healthy individuals to assess safety and feasibility before expanding to stroke populations. The LegExoNET has the potential to enhance gait recovery and reduce therapist burden through error augmentation and personalized support, both in clinical and at-home settings.
Interventions
- Other Assist
The device will provide assistive torques to support either ankle, knee, and/or hip movements. - Other Resist
The device will apply resistive torques to exaggerate gait asymmetries, facilitating error augmentation. - Other Slack
The device will be worn but will not generate any torque.
Primary outcome measures
- Electromyography (EMG) amplitude during walking under each intervention condition [Time frame: Day 1 (single study visit); Measured during each intervention condition (Assist, Resist, Sham)]
Secondary outcome measures (3)
- 6 Minute Walk Test [Time frame: Day 1 (single study visit); Measured during each intervention condition (Assist, Resist, Sham)]
- 10 Meter Walk Test [Time frame: Day 1 (single study visit); Measured during each intervention condition (Assist, Resist, Sham)]
- Gait Symmetry [Time frame: Day 1 (single study visit); Measured during each intervention condition (Assist, Resist, Sham)]
Eligibility criteria
Inclusion criteria
- Age 18-70 years old
- Ability to provide informed consent
- Capable of ambulating without the use of assistive devices for 2 hours
Exclusion criteria
- History of stroke, SCI, or other neurological medical diagnoses
- Pregnant
- Severe medical diagnoses (e.g. cardiovascular, orthopedic)
- Skin allergies or irritation; open wounds
- Prisoners
- Cognitively impaired adults
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Crossover
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06999213 · STU00223221