Integrated Recovery Program for Critical Illness
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: LINE Bot-Based Remote Care Combined with In-Person Post-ICU Clinic.
- Who it may be relevant to
- Registry conditions: ICU Survivors. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Taiwan
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Integrated Critical Illness Aftercare and Recovery Enhancement (I-CARE) Program
Overview
This study aims to investigate the effects of the Integrated Critical Illness Aftercare and Recovery Enhancement (I-CARE) program on reducing healthcare burden and improving functional outcomes in ICU survivors. The I-CARE program combines remote support via LINE Bot Care with in-person post-ICU recovery clinic visits. The study will assess whether this integrated care model reduces unplanned hospital readmissions and emergency department visits within six months after discharge, and improves physical and cognitive outcomes at 3 and 6 months post-discharge. Additionally, the study will evaluate the impact of a built-in patient-nurse interaction feature on ICU nurses' burnout and intention to leave, measured every six months over a two-year period.
Detailed description
This randomized clinical trial is designed to evaluate the effectiveness of the Integrated Critical Illness Aftercare and Recovery Enhancement (I-CARE) program for survivors of critical illness discharged from the intensive care unit (ICU). The I-CARE program integrates a LINE Bot-based remote monitoring and support system with structured, in-person post-ICU recovery clinic visits. The primary objective is to determine whether this comprehensive care model can reduce the incidence of unplanned hospital readmissions and emergency department visits within six months after hospital discharge.
Secondary outcomes focus on functional recovery and include assessments of physical mobility (e.g., ability to transition from sit to stand), inspiratory muscle strength, body weight changes, presence of dysphagia, and cognitive function at 3 and 6 months post-discharge.
In addition, the LINE Bot Care system incorporates an interactive feature titled "Thanks to Nurses," which enables ICU survivors to share personal reflections, such as short messages, photos, diary entries, stickers, and audio clips, with their ICU care team. This bidirectional communication channel is intended to enhance emotional support and foster a sense of connection between patients and healthcare providers. The study will evaluate the impact of this feature on ICU nurses' professional well-being, specifically measuring levels of burnout and intention to leave the profession at 6, 12, 18, and 24 months after implementation, using a pre-post intervention design.
Interventions
- Behavioral LINE Bot-Based Remote Care Combined with In-Person Post-ICU Clinic
Participants in this group will receive the I-CARE intervention, which includes two components: (1) a LINE Bot-based remote care system providing scheduled health education, functional assessments, and reminders tailored to ICU survivors, and (2) structured in-person visits to a post-ICU recovery clinic, where multidisciplinary professionals provide follow-up assessments and individualized rehabilitation guidance. The LINE Bot also features an interactive module ("Thanks to Nurses") that allows
Primary outcome measures
- Incidence of unplanned hospital readmissions [Time frame: 1, 2, 3, 4, 5, and 6 months after discharge]
- Incidence of emergency department visits [Time frame: 1, 2, 3, 4, 5, and 6 months after discharge]
Secondary outcome measures (11)
- Barthel Index [Time frame: Immediately after ICU discharge and 0, 3, and 6 months after discharge]
- Maximal inspiratory pressure [Time frame: Immediately after ICU discharge and 0, 3, and 6 months after discharge]
- Grip strength [Time frame: Immediately after ICU discharge and 0, 3, and 6 months after discharge]
- Modified 30-second sit-to-stand test [Time frame: Immediately after ICU discharge and 0, 3, and 6 months after discharge]
- Montreal Cognitive Assessment [Time frame: Immediately after ICU discharge and 0, 3, and 6 months after discharge]
- Confusion assessment methods [Time frame: Immediately after ICU discharge and 0, 3, and 6 months after discharge]
- Body weight [Time frame: Immediately after ICU discharge and 0, 1, 2, 3, 4, 5, and 6 months after discharge]
- Calf circumference [Time frame: Immediately after ICU discharge and 0, 1, 2, 3, 4, 5, and 6 months after discharge]
- Maslach Burnout Inventory - Human Services Survey (MBI-HSS) [Time frame: 0, 6, 12, 18, and 24 months after I-CARE program start]
- Intention to leave [Time frame: 0, 6, 12, 18, and 24 months after I-CARE program start]
- Mortality rate [Time frame: 1, 2, 3, 4, 5, and 6 months after discharge]
Eligibility criteria
Inclusion criteria
- ICU survivors who had experienced endotracheal intubation and mechanical ventilation treatment.
Exclusion criteria
- ICU survivors who are unable to walk independently before admission
- ICU survivors who are unable to receive assessment (e.g., dementia or mental retardation)
- ICU survivors who don't have a smartphone.
- ICU survivors were discharged to institutional care facilities
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Prevention
Study locations
Taiwan · 1 center
- National Taiwan University Hospital — Taipei
Identifiers
NCT: NCT06997822 · 202502049RINA