UEMR Versus HSP in the Treatment of Pedunculated Colorectal Polyps Less Than 10mm in Size
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: underwater endoscopic mucosal resection, Hot snare polypectomy.
- Who it may be relevant to
- Registry conditions: Pedunculated Colorectal Polyp. Basic parameters: 35 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Underwater Endoscopic Mucosal Resection Versus Hot Snare Polypectomy in the Treatment of Pedunculated Colorectal Polyps Less Than 10mm in Size: A Single-center, Open-label, Randomized Controlled Trial
Overview
A prospective, single-center, open-label, randomized controlled study to compare the effectiveness and safety of underwater endoscopic mucosal resection (UEMR) and hot snare polypectomy (HSP) in treating Pedunculated colorectal polyps less than 10mm in size.
Detailed description
1. Patients are undergone screening, surveillance, or therapeutic colonoscopy at the Endoscopy department of Gastrointestinal endoscopy center of Huadong hospital affiliated to Fudan University. 2. Randomize patients with pedunculated colorectal polyps less than 10mm in size into 2 interventional groups based on Random function of Statistical Package for the Social Sciences (SPSS) 20.0, including (1) Group 1: Underwater endoscopic mucosal resection (UEMR) and (2) Group 2: Hot snare polypectomy (HSP). 3. Collecting variables which consist of primary and secodary outcomes.
Interventions
- Procedure underwater endoscopic mucosal resection
The Pedunculated colorectal polyps less than 10mm in size in this group will be treated by UEMR - Procedure Hot snare polypectomy
The Pedunculated colorectal polyps less than 10mm in size in this group will be treated by HSP
Primary outcome measures
- Post-polypectomy Bleeding [Time frame: 2 weeks after the procedure]
Secondary outcome measures (4)
- postoperative electrocoagulation syndrome [Time frame: 2 weeks after the procedure]
- en bloc resection [Time frame: immediately after the procedure]
- R0 resection [Time frame: 2 weeks after the procedure]
- Delayed perforation [Time frame: 2 weeks after the procedure]
Eligibility criteria
Inclusion criteria
- Aged between 35 and 80 years
- Pedunculated colorectal polyps less than 10mm in size in screening, surveillance or therapeutic colonoscopy
- 0-Isp or 0-Ip according to Paris classification
- Patients must sign an informed consent form prior to registration in study
Exclusion criteria
- Unsuitable for removal by UEMR or HSP
- Suspected malignancy
- History of inflammatory bowel disease or colorectal resection
- Familial adenomatous polyposis or Lynch syndrome
- Patients taking anticoagulant and antiplatelet agents before the examination
- Inadequate bowel preparation, defined as a Boston Bowel Preparation Scale score < 6
- ASA >=3
- Pregnancy or breastfeeding
- Severe comorbid disease involving the heart, lungs, liver, or kidneys.
- Concurrent serious conditions, including other active malignancies or severe infectious diseases
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
China · 1 center
- Huadong hospital affiliated to Fudan university — Shanghai
Identifiers
NCT: NCT06996522 · 2025K132