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Not yet recruiting NCT06995417

Discontinuation of Tobacco Dependence in Smoking Patients With Squamous Cell Carcinoma of the Head-neck District: Multicenter Prospective Observational Study

Observational Cancer of Head and Neck

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Smoking counseling.
Who it may be relevant to
Registry conditions: Cancer of Head and Neck. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Italy
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The primary objective of our study is to evaluate the effectiveness of a standardized clinical practice counseling strategy for promoting post-diagnosis smoking cessation among patients with SCCHN. Efficacy will be measured as the percentage of patients who succeed in sustained smoking cessation ("sustained quitters," see below) at 6+1 months after enrollment, i.e., after the initiation of anti-smoking counseling.

Interventions

  • Other Smoking counseling
    The investigator, upon enrollment, will initiate a standardized strategy from clinical practice: the investigator will conduct brief counseling ("minimal advice") using the administration of of a questionnaire that will include, in addition to questions about current and past, the administration of the Fagerstrom test to measure physical dependence on nicotine and questions to investigate intention to quit smoking (Mondor test)

Primary outcome measures

  • Effectiveness of a standardized counseling strategy in clinical practice to promote smoking cessation [Time frame: 6+1 months from enrollment, i.e., initiation of anti-smoking counseling.]

Eligibility criteria

Inclusion criteria.

  • Patients with SCCHN tumors of the oral cavity, oropharynx, hypopharynx, larynx, nasopharynx, and paranasal sinuses.
  • Patients older than 18 years of age with SCCHN of these sites who are candidates for surgical/radiotherapy (RT)/radiochemotherapy (RTCT) treatment with curative intent (primary treatment).
  • Patients with SCCHN who are active smokers, or have quit smoking for less than 30 days, at the time of initiation of the process (visits and instrumental tests) that led to the diagnosis of cancer

Exclusion criteria

  • Patients with SCCHN cancer who have quit smoking for more than 30 days at the time of initiation of the diagnostic process.
  • Patients using only e-cigarettes at the time of initiation of the treatment process.
  • Patients with non-SCCHN cancer in recurrent metastatic stage and not eligible for curative purpose therapy.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Case-only

Study locations

Italy · 1 center
  • Azienda Ospedaliera Careggi — Florence

Identifiers

NCT: NCT06995417 · STOP-HNC

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗