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Not yet recruiting NCT06995404

Transversus Abdominis Plane Block (TAP) Versus Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) in Laparoscopic Gynecologic Surgeries

No phase Interventional Gynecologic Laparoscopic Surgery Regional Anesthesia Block

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: TAP Block Group, M-TAPA Block group.
Who it may be relevant to
Registry conditions: Gynecologic Laparoscopic Surgery, Regional Anesthesia Block. Basic parameters: 18 years — 80 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

Although laparoscopic techniques are considered minimally invasive surgical procedures with lower perioperative pain scores compared to open surgeries, they are still associated with significant levels of pain. This study aims to investigate the analgesic effectiveness of two routinely performed regional analgesic techniques in our clinic-ultrasound-guided classic bilateral TAP block and ultrasound-guided bilateral M-TAPA block-in patients undergoing laparoscopic gyneco-oncologic surgery (LGOS), as well as their effects on intraoperative opioid consumption.

Interventions

  • Procedure TAP Block Group
    Patients in the TAP group will receive a bilateral Transversus Abdominis Plane (TAP) block under ultrasound guidance prior to surgery after general anaesthesia, with the local anesthetic administered between the internal oblique and transversus abdominis muscles. A total of 40 mL of 0.25% bupivacaine will be used for the procedure.
  • Procedure M-TAPA Block group
    Patients in the M-TAPA group will receive a bilateral Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) under ultrasound guidance prior to surgery after general anaesthesia. A total of 40 mL of 0.25% bupivacaine will be used for the procedure.

Primary outcome measures

  • Evaluation of intraoperative opioid consumption [Time frame: during surgery]
Secondary outcome measures (1)
  • Comparison of postoperative Visual Analog Scale (VAS) pain scores [Time frame: postoperative first day]

Eligibility criteria

Inclusion Criteria:Female patients aged between 18 and 80 years, classified as ASA physical status I to III, undergoing laparoscopic gynecologic surgery under general anesthesia -

Exclusion Criteria:Coagulopathy

Neuropathy

Chronic analgesic therapy

Severe cardiopulmonary disease

Uncontrolled diabetes mellitus (HbA1c > 8%)

Severe renal or hepatic failure

Pregnancy or lactation

Body mass index (BMI) greater than 35 kg/m²

Local infection at the injection site

Inability to comprehend pain scores or cooperate (e.g., Alzheimer's disease, mental retardation)

Allergy to local anesthetic agents

Refusal to participate in the study

\-

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Triple blind
Primary purpose
Treatment

Study locations

Turkey (Türkiye) · 1 center
  • Ankara Etlik City Hospital — Ankara

Identifiers

NCT: NCT06995404 · AESH-EK-2025-028

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗