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Not yet recruiting NCT06995365

Refining Risk Prediction Models for Older Adults Using Electronic Health Records

Observational Predictive Modeling

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Risk Prediction Model.
Who it may be relevant to
Registry conditions: Predictive Modeling. Basic parameters: from 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Patient-centered Precision Medicine Lab Result Communication for Older Adults - Validation and Refinement of an Existing Chronic Kidney Disease (CKD) Risk Model

Overview

This study aims to improve how lab results are communicated to older adults by refining a predictive model that uses electronic health record (EHR) data. The model was originally developed to estimate the risk of chronic kidney disease (CKD) progression. Researchers will use existing health data to test and improve the accuracy of the model and explore how it might be adapted for use in other health conditions. The study does not involve direct interaction with patients and is conducted entirely using de-identified data in a secure environment.

Interventions

  • Other Risk Prediction Model
    This study analyzes retrospective electronic health record (EHR) data from older adults to refine and validate a predictive model for other conditions in future studies.

Primary outcome measures

  • Performance of the Risk Prediction Model [Time frame: Up to 5 years of retrospective follow up]

Eligibility criteria

Inclusion Criteria include, but are not limited to:

  • being over the age of 65; having at least 5 years of clinical follow up; and having a serum creatinine lab test conducted

Exclusion criteria

  • Patients younger than 65 years old
  • Patients with less than 5 years of clinical follow-up
  • Patients from health systems outside of the UC Health network.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United States · 1 center
  • UCLA Health System — Los Angeles

Identifiers

NCT: NCT06995365 · IRB-26-1370

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗