Comparison of G-CSF & Antibiotics Versus Antibiotics Alone in Resolution of Febrile Neutropenia
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: G-CSF, Antibiotics only.
- Who it may be relevant to
- Registry conditions: Febrile Neutropenia, Febrile Neutropenia, Rule of Clinical Decision, Chemotherapy, Febrile Neutropenia, Drug-Induced, G-CSF. Basic parameters: 1 year — 16 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Comparison of Antibiotics With and Without Granulocyte Colony-Stimulating Factor in Children With Chemotherapy Induced Febrile Neutropenia
Overview
This study aim to find the best option for children having cancer who develop low immunity state due to chemotherapy
Detailed description
Children having a cancer diagnosis and treated with chemotherapy often develop neutropenia. This creates an immunocompromised state which can result in infections manifested by fever. This study compares two treatment options to find out the best treatment for these patients.
Interventions
- Drug G-CSF
G-CSF \& Antibiotic therapy in combination - Drug Antibiotics only
Antibiotics alone
Primary outcome measures
- Resolution of FN [Time frame: 2 weeks]
Secondary outcome measures (2)
- Afebrile [Time frame: 2 weeks]
- Length of hospital stay [Time frame: 2 weeks]
Eligibility criteria
Inclusion criteria
- Age 1-16 years
- any Gender
- Febrile neutropenia
- diagnosed case of solid or hematological malignancy
- taking chemotherapy
Exclusion criteria
- Non-neutropenic fever
- already received G-CSF or antibiotics before presenting to hospital
- any other cause of neutropenia
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06988826 · 656/CH-UCHS/15/5/2023