Glycemic Control Following Occupational Work in a Hot Environment
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Hot environment, Temperate condition.
- Who it may be relevant to
- Registry conditions: Plasma Glucose Following Prolonged Heat Exposure. Basic parameters: 18 years — 45 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Occupational workers regularly perform physically demanding tasks in hot environments, exposing them to heat stress and potential dehydration. While the physiological impacts of heat exposure are well-documented, its effects on glycemic control remain less understood. Given the rising global temperatures due to climate change and the increasing prevalence of metabolic disorders such as obesity and type 2 diabetes, it is essential to investigate how heat exposure during work influences glycemic regulation. Understanding these interactions will help inform future occupational health guidelines and metabolic health recommendations in physically demanding industries.
Interventions
- Other Hot environment
Participants exercising in a 36 degrees celsius environment - Other Temperate condition
Participants exercising in a 18 degrees celsius environment
Primary outcome measures
- Plasma glucose [Time frame: 8hours]
Secondary outcome measures (12)
- Plasma insulin [Time frame: 8hours]
- Plasma osmolality [Time frame: 8hours]
- Plasma volume change [Time frame: 8hours]
- Urine volume [Time frame: 8hours]
- Body mass [Time frame: 8hours]
- Urine specific gravity/osmolality [Time frame: 8hours]
- Rectal temperature [Time frame: 8hours]
- Blood pressure [Time frame: 8hours]
- Respiratory gas exchanges [Time frame: 8hours]
- Rate of perceived exertion [Time frame: 8hours]
- Rate of thermal sensation [Time frame: 8hours]
- Feelings of thirst, urge to urinate, GI comfort, and stomach bloatedness [Time frame: 8hours]
Eligibility criteria
Inclusion criteria
- Male or female
- Generally fit and healthy
- Participate in endurance or intermittent exercise at least 3 times a week or minimum of 150 minutes moderate intensity activity per week
Exclusion criteria
- Under 18 or 45 and over,
- any morbidity or medication that might influence carbohydrate/fat metabolism (i.e., liver/renal/cardiovascular disease) or cycling ability (musculoskeletal injury etc),
- coagulation or bleeding disorders,
- blood-borne illness,
- heart conditions,
- congenital heart disease,
- uncontrolled exercise-induced asthma,
- smoking (including vaping),
- allergies to the products used in the study,
- dieting or restrained eating behaviours.
- Females with amenorrhea would be an exclusion criteria.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Crossover
- Masking
- Single blind
- Primary purpose
- Basic science
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06982612 · LEON21544