Comparison of Quadriceps and Semitendinosus Grafts in ACL Reconstruction Using Data From the Danish Knee Ligament Reconstruction Registry (DKRR)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Anterior Cruciate Ligament Injury, Knee Injury, Ligament Reconstruction, Sports Injuries. Basic parameters: 15 years — 50 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Denmark
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
ACL Reconstruction With Quadriceps Tendon Graft vs. Quadrupled Semitendinosus Graft: A Comparison of Patients From the Danish National ACL Reconstruction Database
Overview
This study looks at two different types of tendon (tissue) used in knee surgery to repair a torn anterior cruciate ligament (ACL), which is a common injury in active people. The two types are taken from different muscles in the thigh: one from the front (quadriceps) and one from the back (semitendinosus). We will use information already collected in a national health registry to see how patients recover after surgery. The study will compare knee function, activity level, and how often patients need another operation.
Detailed description
This is a retrospective observational cohort study based on data from the Danish Knee Ligament Reconstruction Registry (DKRR). The study includes patients who underwent primary ACL reconstruction using either a quadriceps tendon graft (with or without a bone block) or a quadrupled semitendinosus tendon graft. The primary outcome measures are the Knee Injury and Osteoarthritis Outcome Score (KOOS) and the Tegner Activity Scale. Secondary outcomes include reoperation rates, postoperative complications, and patient satisfaction. All available demographic, operative, and patient-reported outcome data will be analyzed. Multivariable regression will be used to adjust for confounders such as age, sex, BMI, time from injury to surgery, and surgeon volume. The study is exempt from ethical approval under Danish law, and data will be handled in compliance with GDPR.
Primary outcome measures
- The Knee Injury and Osteoarthritis Outcome Score (KOOS) [Time frame: At minimum 1 year follow up postoperatively]
- Tegner Activity Score [Time frame: Minimum 1 year follow up postoperatively.]
Secondary outcome measures (3)
- Re-operation rate [Time frame: Within 1 year of surgery]
- Postoperative complications [Time frame: Within 1 year after surgery]
- Patient satisfaction [Time frame: 1 year follow up]
Eligibility criteria
Inclusion criteria
- Primary ACL reconstruction registered in the Danish Knee Ligament Reconstruction Registry (DKRR)
- Known graft type: quadriceps tendon or semitendinosus tendon Minimum 1-year follow-up with completed patient-reported outcome measures (KOOS and/or Tegner score)
- Age between 15 and 50 years at the time of surgery (optional subgroup analysis)
Exclusion criteria
- Revision ACL reconstruction
- Multiligament knee reconstruction
- Missing or incomplete PROMs or key clinical data
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Denmark · 1 center
- Søernes Privathospital — Copenhagen
Identifiers
NCT: NCT06980285 · SOPH-ACL-3+25