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Recruiting NCT06976320

Deep Rectus Sheath Block for Laparoscopic Cholecystectomy

No phase Interventional Cholecystectomy, Laparoscopic Anesthesia Postoperative Pain

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Intravenous morphine patient control analgesia, Intravenous patient control analgesia, Deep rectus sheath block.
Who it may be relevant to
Registry conditions: Cholecystectomy, Laparoscopic, Anesthesia, Postoperative Pain. Basic parameters: 18 years — 80 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Deep Rectus Sheath Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy

Overview

Postoperative pain after laparoscopic cholecystectomy can be considerable. Regional techniques such as erector spinae plane (ESP) block or transversus abdominis plane (TAP) block may be suitable for patients at increased risk of postoperative pain. The deep rectus sheath block is a novel block which is a modified version of the conventional rectus sheath block. It was reported in a few case reports that, it may be used for postoperative analgesia in patients undergoing laparoscopic cholecystectomy. The aim of this study is to investigate the postoperative analgesic efficacy of deep rectus sheath block in patients undergoing laparoscopic cholecystectomy.

Detailed description

Patients scheduled for elective laparoscopic gastrectomy will be separated into 2 groups: Control Group and Deep Rectus Sheath Block Group. Patients in Control Group will be received patient controlled analgesia with morphine for postoperative analgesia. Patients in Deep Rectus Sheath Block Group will be performed Deep Rectus Sheath Block at the end of the surgery, along with patient controlled analgesia with morphine for postoperative analgesia. Morphine consumption for first postoperative 24 hours, numerical rating scale scores, amount of rescue analgesic drug, incidence of postoperative nausea and vomiting will be recorded.

Interventions

  • Other Intravenous morphine patient control analgesia
    24-hour morphine consumption will be recorded
  • Other Intravenous patient control analgesia
    24-hour morphine consumption will be recorded
  • Other Deep rectus sheath block
    Deep rectus sheath block will be administered at the end of the surgery.

Primary outcome measures

  • Morphine consumption [Time frame: Postoperative 24 hours]
Secondary outcome measures (3)
  • Postoperative numerical rating scale scores [Time frame: Postoperative 24 hours]
  • Rescue analgesic drug requirement [Time frame: Postoperative 24 hours]
  • Incidence of postoperative nausea and vomiting [Time frame: Postoperative 24 hours]

Eligibility criteria

Inclusion criteria

  • Age between 18 and 80 years
  • Patients with American Society of Anesthesiology (ASA) physical status I-II
  • Patients scheduled for a laparoscopic cholecystectomy

Exclusion criteria

  • Allergy to local anesthetics
  • Coagulopathy
  • Skin infection at the deep rectus sheath block area
  • Advanced hepatic or renal failure
  • Chronic pain syndromes
  • Alcohol or drug abuse
  • Severe pulmonary and/or cardiovascular disease
  • Psychiatric disorders

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Other

Study locations

Turkey (Türkiye) · 1 center
  • Istinye University Hospital — Istanbul

Publications

  • Kavakli AS, Bozkurt MA, Diri M, Sahin T, Koc U, Ipek ZSK, Cekem A. Preperitoneal analgesia under direct visualization: laparoscopic-guided deep rectus sheath block improves postoperative pain control after laparoscopic cholecystectomy: a randomized controlled trial. Surg Endosc. 2026 Jun 16. doi: 10.1007/s00464-026-12973-5. Online ahead of print. PMID 42303918

Identifiers

NCT: NCT06976320 · Anestezi4

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗