A Twenty-years' Experience in Pituitary Disease.
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Frequency of disease recurrence.
- Who it may be relevant to
- Registry conditions: Pituitary Adenoma, Pituitary Cancer, Pituitary Disease. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
A Twenty-years' Experience in Pituitary Disease: Identification of Prognostic Factors in Pituitary Tumors
Overview
Pituitary tumors represent a heterogeneous group of neoplasms by histotype. The pituitary adenomas are the most frequent heteroformation, among those affecting the pituitary gland, followed by meningiomas, craniopharyngiomas, germosomes and tumours secondary, such as metastases and lymphomas. Since these conditions are considered rare, the data epidemiology and prognosis to predict the natural history of these diseases can not be considered conclusive. Pituitary adenomas are a useful model for epidemiology in the study of pathology pituitary. Over the past 20 years, several attempts have been made to identify unique prognostic factors, which predict the outcome of these pathologies, but without To arrive at a definitive classification. The purpose of this study aims to collect clinical, biochemical, morphological and pathological data on the retrospective and prospective cohort of over 1600 patients undergoing neurosurgical removal of pituitary tumors in the last 20 years, to develop a prognostic classification.
Interventions
- Other Frequency of disease recurrence
To collect data of pituitary disease recurrence
Primary outcome measures
- Tumor recurrence [Time frame: From enrollement to last observation at 24 months of follow-up]
Eligibility criteria
Inclusion criteria
- Patients underwent surgery for pituitary tumors;
- pathology diagnosis of pituitary tumors;
- patients older then 18 years at diagnosis of pituitary tumors;
- 2 years follow-up;
Exclusion criteria
- age lower then 18 years
- follow-up shorter than 2 years
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Italy · 1 center
- Fondazione Policlinico Gemelli IRCCS — Rome
Identifiers
NCT: NCT06973824 · 6546