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Recruiting NCT06971575

Cervical Radiculopathy Imaging Using MRN With Electrodiagnostic Correlation

— Observational Cervical Radiculopathy

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Magnetic resonance neurography.
Who it may be relevant to
Registry conditions: Cervical Radiculopathy. Basic parameters: 18 years — 60 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Cervical Radiculopathy Imaging Using MR Neurography With Electrodiagnostic Correlation

Overview

This project will study patients with cervical radiculopathy. We will evaluate the combined diagnostic and prognostic value of magnetic resonance neurography (MRN), electrodiagnostic (EDX) studies, and historical and physical clinical elements. Specifically, this project will explore whether these data individually or in combination correlate with response to procedural and non-procedural treatment.

Interventions

  • Diagnostic test Magnetic resonance neurography
    Patients will undergo a cervical MRI with specialized magnetic resonance neurography sequences to evaluate the extraforaminal cervical nerve roots.

Primary outcome measures

  • Presence of abnormalities on nerve (MRN) imaging [Time frame: Baseline]
  • Relationship between abnormalities on imaging and electrodiagnostic assessment [Time frame: Baseline]
Secondary outcome measures (2)
  • Numeric rating scale (NRS) pain [Time frame: Baseline, 3 months, 6 months, 12 months]
  • Neck Disability Index (NDI) [Time frame: Baseline, 3 months, 6 months, 12 months]

Eligibility criteria

Inclusion criteria

  • Patients presenting with symptoms compatible with acute or subacute unilateral (one-sided) cervical radiculopathy and signs of clinical weakness
  • 18-60 years old at the time of evaluation
  • Symptom onset of 2 to 12 weeks leading up to baseline visit
  • Diagnosis of unilateral cervical radiculopathy, with or without spinal cord compression, based on signs and symptoms, physical exam and supported by MRI findings of radiculopathy (as evidenced by foraminal stenosis/narrowing) based on standard-of-care cervical spine MRI
  • Patients who have undergone or have planned electrodiagnostic testing at HSS prior to surgery

Exclusion criteria

  • Prior cervical surgery or instrumentation
  • Those who have had a prior episode of cervical radiculopathy
  • History of peripheral neuropathy or another acute or chronic neurodegenerative condition
  • History of stroke, cerebellar disease, or central nervous system disease
  • Contraindications to undergoing a standard MRI examination (e.g., pregnancy)
  • Patients presenting with bilateral cervical radiculopathy

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United States · 1 center
  • Hospital for Special Surgery — New York

Identifiers

NCT: NCT06971575 · 2023-1447

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗