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Enrolling by invitation NCT06965842

The Video System to Provide a Developmental Training Guide for Preterm Infants

No phase Interventional Premature Infants Very Low Birth Weight Infants

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Parent-centered developmental training.
Who it may be relevant to
Registry conditions: Premature Infants, Very Low Birth Weight Infants. Basic parameters: up to 1 months · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
South Korea
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Video System to Provide a Developmental Training Guide for In-home, Parent-centered, Early Intervention in Preterm Infants: A Proof of Concept and Feasibility Study

Overview

This study aimed to establish a systematic developmental training guide protocol for parent-centered early intervention and verify the concept and feasibility of a video system for parent-centered in-home developmental therapy under the monitoring of a therapist. The target group is premature infants under 32 weeks of gestation or very low birth weight infants under 1500 g with brain damage. A single-arm intervention group of 10 people was recruited, and considering a dropout rate of 20%, the total number of participants was calculated to be 12. 1:1 monitoring to provide parent-centered early intervention at home after discharge from the neonatal intensive care unit is conducted twice a week for 30 minutes per session using a video platform (Zoom) until the corrected age of 6 months. Parents record the developmental training process using a smartphone and transmit it to the therapist, who analyzes the video data to provide new treatment goals and guidelines. Feasibility assessment included: 1) Exercise diary: Number of total and average sessions performed (N) and percentage (%), number of total and average sessions completed (N) and percentage (%) 2) Parent questionnaire 3) Video analysis: Periodic video education and developmental training video acquisition and analysis 4) Heart rate analysis: Analysis of average heart rate during and after rest and developmental training 5) Safety analysis: Number of times (N) and reasons for exercise interruption during developmental training 6) Developmental assessment: Implementation of developmental assessments such as GMOS, MOS-R, HINE, GMFM, and BSID. For safety assessment, if the following symptoms appear during development training, stop exercising and rest until stable. If oxygen saturation drops by more than 10% compared to resting, causing cyanosis and dyspnea, or if heart rate increases by more than 150 beats/min.

Interventions

  • Other Parent-centered developmental training
    After discharge from the neonatal intensive care unit, 1:1 monitoring is conducted at home for 30 minutes twice a week using a video conferencing platform (Zoom) until the corrected age of 6 months to provide parent-centered early intervention. Parents film the developmental training process using a smartphone and send the video to the therapist, who analyzes the video data to provide new treatment goals and guidelines.

Primary outcome measures

  • Number of total and average sessions performed (N) [Time frame: up to corrected age 6 months]
  • Percentage of total and average sessions performed (%) [Time frame: up to corrected age 6 months]
  • Number of total and average sessions completed (N) [Time frame: up to corrected age 6 months]
  • Percentage of total and average sessions completed (%) [Time frame: up to corrected age 6 months]
  • Parent questionnaire [Time frame: at corrected age 6 months]
  • General Movement Optimality Score [Time frame: corrected age 0, 1.5months]
  • Motor Optimality Score-Revised [Time frame: corrected age 4months]
  • Hammersmith Infant Neurological Examination [Time frame: corrected age 4, 6, 9 months]
  • Gross Motor Function Measure [Time frame: corrected age 6, 9 months]
  • Bayley Scales of Infant and Toddler Development [Time frame: corrected age 9 months]

Eligibility criteria

Inclusion criteria

  • Premature infants less than 32 weeks of gestation or extremely low birth weight infants less than 1500 g
  • Premature infants with a corrected age of less than 1 month
  • Brain damage through brain imaging (e.g. cranial USG, brain MRI)

Exclusion criteria

  • Multiple malformations or genetic abnormalities
  • Severe visual or hearing impairment
  • Loss of consciousness
  • Tracheostomy
  • Medically unstable condition

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Health services research

Study locations

South Korea · 1 center
  • Seoul National University Hospital — Seoul

Identifiers

NCT: NCT06965842 · 0420222050

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗