Enrolling by invitation NCT06964152
Computational Cardiac Imaging Analysis to Guide Ventricular Tachycardia Ablation Procedures (AI-VT)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Computational electrocardiography and cardiac computed tomography mapping.
- Who it may be relevant to
- Registry conditions: Ventricular Tachycardia (VT), Premature Ventricular Contraction (PVC), Ventricular Fibrillation. Basic parameters: 21 years — 90 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Prospective Use of Computational Cardiac Imaging Analysis to Guide Ventricular Tachycardia Ablation Procedures (AI-VT)
Overview
The purpose of this study is to evaluate the clinical outcomes (clinical efficacy and safety) of using supplemental non-invasive computational ECG and cardiac imaging analysis tools to help guide ablation of ventricular tachycardia.
Interventions
- Diagnostic test Computational electrocardiography and cardiac computed tomography mapping
Use of non-invasive computational ECG and cardiac CT models to localize arrhythmia origins
Primary outcome measures
- Recurrent ventricular tachycardia [Time frame: 1 year]
- All-cause death [Time frame: 1 year]
Secondary outcome measures (5)
- Acute hemodynamic decompensation [Time frame: 24 hours post-op]
- Unplanned prolonged ICU upgrade [Time frame: 48 hours]
- acute cerebrovascular accident (embolic) [Time frame: 24 hours post-op]
- acute pericardial tamponade requiring intervention [Time frame: 24 hours post-op]
- vascular complication requiring intervention [Time frame: 24 hours post-op]
Eligibility criteria
Inclusion criteria
- Age between 21 and 100
- Evidence of ventricular tachycardia on ECG, telemetry or by CIED interrogation.
Exclusion criteria
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Diagnostic
Study locations
United States · 1 center
- UC San Diego Health — La Jolla
Publications
- Krummen DE, Villongco CT, Ho G, Schricker AA, Field ME, Sung K, Kacena KA, Martinson MS, Hoffmayer KS, Hsu JC, Raissi F, Feld GK, McCulloch AD, Han FT. Forward-Solution Noninvasive Computational Arrhythmia Mapping: The VMAP Study. Circ Arrhythm Electrophysiol. 2022 Sep;15(9):e010857. doi: 10.1161/CIRCEP.122.010857. Epub 2022 Sep 7. PMID 36069189
Identifiers
NCT: NCT06964152 · 171964