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Recruiting NCT06962995

Multi-Cancer Detection Observational Cohort Study

— Observational Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Blood Sample, Surveys.
Who it may be relevant to
Registry conditions: Cancer. Basic parameters: from 21 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

This study assesses the incorporation of Multi-Cancer Detection (MCD) testing, designed to detect many types of cancer, into clinical practice to understand both its use and effect in real world practice conditions.

Interventions

  • Procedure Blood Sample
    Up to 60 mL (about 4-5 Tbsp) of blood may be collected for an initial blood draw and up to 30 mL (about 2-3 Tbsp) may be collected for a second blood draw, 25-45 days after first blood draw. The research blood will be collected at the time of a clinical blood draw, if possible.
  • Other Surveys
    Participants will complete surveys related to attitudes and beliefs around Multi-Cancer Detection testing.

Primary outcome measures

  • Financial impact of MCD testing [Time frame: Up to 5 years]
  • Positive actionable MCD results [Time frame: Up to 5 years]
  • Psychological Impact of MCD Testing [Time frame: Baseline (after receiving MCD results)]
  • Change in Patient Satisfaction with MCD Test [Time frame: Baseline; After receiving MCD results (up to 5 years)]

Eligibility criteria

Inclusion criteria

  • Has Mayo Clinic medical record number
  • Has undergone (within last 6 months) or scheduled to undergo a multi-cancer detection test (MCD) as ordered by provider
  • Able to provide informed consent
  • ≥ 21 years old
  • Ability to provide blood sample

Exclusion criteria

  • Individuals who have situations that would limit compliance with the study requirements
  • Institutionalized (i.e. Federal Medical Prison)
  • Known pregnancy (self-reported)
  • Currently undergoing active cancer treatment other than adjuvant hormone therapy
  • Invasive cancer diagnosis within the last 3 years

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

United States · 3 centers
  • Mayo Clinic in Arizona — Scottsdale
  • Mayo Clinic in Florida — Jacksonville
  • Mayo Clinic in Rochester — Rochester

Identifiers

NCT: NCT06962995 · 24-000321 · R01CA214679

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗