Not yet recruiting NCT06962878
Assessment of Bone Volume Changes in Immediate Implant Placement Using Allograft Versus Xenograft in Mandibular Molars
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Xenograft, Allograft.
- Who it may be relevant to
- Registry conditions: Bone Volume, Immediate Implant With Bone Graft. Basic parameters: 25 years — 40 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Assessment of Bone Volume Changes in Immediate Implant Placement Using Allograft Versus Xenograft in Mandibular Molars: Randomized Clinical Trial
Overview
Twenty recruited patients indicated for immediate implant placement in mandibular molar sites are divided into two groups, with each group containing ten patients. One group assigned for placement of xenograft after molar extraction and immediate implant placement, while the other group received allograft as space-filling material.
Interventions
- Procedure Xenograft
The jumping gap and surrounding space will be augmented and packed with Xenograft - Procedure Allograft
The jumping gap and surrounding space will be augmented and packed with Allograft
Primary outcome measures
- Horizontal bone thickness in millimeters [Time frame: 6 months postoperative]
Secondary outcome measures (2)
- Vertical bone height in millimeters [Time frame: 6 months postoperative]
- Pain intensity [Time frame: One week postoperative]
Eligibility criteria
Inclusion criteria
- Patients with non-restorable mandibular molars
- Both sexes with age range from 25 years to 40 years
- Good oral hygiene
- Adequate alveolar bone dimensions for implant replacement
- Adequate bone volume after extraction to achieve primary stability of the immediate implant
- Co-operative patient
Exclusion criteria
- Patients with any systemic disease as uncontrolled diabetes or osteoporosis
- Heavy smokers with smokers more than 10 cigarettes per day
- Pregnancy
- Patients with any signs of active infection or pus formation
- Patients undergoing chemotherapy or radiotherapy, immunocompromised patients
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Faculty of Dentistry, Cairo University — Cairo
Publications
- Botticelli D, Berglundh T, Buser D, Lindhe J. The jumping distance revisited: An experimental study in the dog. Clin Oral Implants Res. 2003 Feb;14(1):35-42. doi: 10.1034/j.1600-0501.2003.140105.x. PMID 12562363
- Bhola M, Neely AL, Kolhatkar S. Immediate implant placement: clinical decisions, advantages, and disadvantages. J Prosthodont. 2008 Oct;17(7):576-81. doi: 10.1111/j.1532-849X.2008.00359.x. Epub 2008 Aug 26. PMID 18761580
- Lang NP, Pun L, Lau KY, Li KY, Wong MC. A systematic review on survival and success rates of implants placed immediately into fresh extraction sockets after at least 1 year. Clin Oral Implants Res. 2012 Feb;23 Suppl 5:39-66. doi: 10.1111/j.1600-0501.2011.02372.x. PMID 22211305
- Dimitriou R, Mataliotakis GI, Angoules AG, Kanakaris NK, Giannoudis PV. Complications following autologous bone graft harvesting from the iliac crest and using the RIA: a systematic review. Injury. 2011 Sep;42 Suppl 2:S3-15. doi: 10.1016/j.injury.2011.06.015. Epub 2011 Jun 25. PMID 21704997
- Khoury F, Hanser T. Mandibular bone block harvesting from the retromolar region: a 10-year prospective clinical study. Int J Oral Maxillofac Implants. 2015 May-Jun;30(3):688-97. doi: 10.11607/jomi.4117. PMID 26009921
- Schropp L, Isidor F. Timing of implant placement relative to tooth extraction. J Oral Rehabil. 2008 Jan;35 Suppl 1:33-43. doi: 10.1111/j.1365-2842.2007.01827.x. PMID 18181932
- Alexopoulou M, Lambert F, Knafo B, Popelut A, Vandenberghe B, Finelle G. Immediate implant in the posterior region combined with alveolar ridge preservation and sealing socket abutment: A retrospective 3D radiographic analysis. Clin Implant Dent Relat Res. 2021 Feb;23(1):61-72. doi: 10.1111/cid.12974. Epub 2021 Jan 13. PMID 33438320
- Howe MS, Keys W, Richards D. Long-term (10-year) dental implant survival: A systematic review and sensitivity meta-analysis. J Dent. 2019 May;84:9-21. doi: 10.1016/j.jdent.2019.03.008. Epub 2019 Mar 20. PMID 30904559
Identifiers
NCT: NCT06962878 · Grafting in immediate implants