Combining Electrical Impedance Tomography and Thoracic Ultrasound Toinvestigate Dynamic Changes
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Electrical impedance tomography.
- Who it may be relevant to
- Registry conditions: ARDS (Moderate or Severe). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Combining Electrical Impedance Tomography and Thoracic Ultrasound to Investigate Dynamic Changes of Respiratory Effort, and Regional & End-expiratory Lung Volume in Mechanically Ventilated Patients.
Overview
1. To evaluate the dynamic changes of lung ultrasound during electrical impedance tomography (EIT) PEEP titration and across the first week of ARDS. 2. To asses respiratory effort by diaphragmatic function, esophageal pressure, and EIT (Pendelluft phenomenon), and hyperinflammatory biomarkers, to predict P-SILI. 3. To develop predictive models for weaning success based on integrated EELI and thoracic ultrasound.
Interventions
- Diagnostic test Electrical impedance tomography
* Electrical impedance tomography (EIT)：Assessing pulmonary function in chronic lung diseases. * Lung ultrasound：Assessing diaphragm atrophy in mechanically ventilated patients. * Esophageal pressure：The work of breathing, or the energy required by respiratory muscles to meet ventilatory demands, can be directly evaluated by esophageal pressure * Oxygen consumption：Indirectly evaluated by measuring oxygen consumption (V̇O2) during mechanical ventilation The oxygen cost of breathing, reflected th
Primary outcome measures
- ARDS [Time frame: From enrollment to the end of treatment at 1 weeks.]
Eligibility criteria
Inclusion criteria
- Adult >18 y/o.
- Patient intubated and receiving mechanical ventilation > 24 hours.
- Admitted into ICU, diagnosed as moderate or severe ARDS (ICD-10-CM: J80) according to Berlin definition.
Exclusion criteria
- Presence of Implanted Electronic Devices (pacemakers, implantable cardioverter-defibrillators).
- Pregnancy.
- No consent/inability to obtain consent and appropriate legal representative not available.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06958770 · 202502091RIND