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Recruiting NCT06957158

The Effect of Serum Calcium Levels on Postoperative Pain: A Prospective Observational Study

— Observational Postoperative Pain

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Peripheral venous blood, Arterial blood.
Who it may be relevant to
Registry conditions: Postoperative Pain. Basic parameters: 18 years — 70 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

The Effect of Serum Calcium Levels on Postoperative Pain in Patients Undergoing Abdominal Surgery: A Prospective Observational Study

Overview

This is a prospective observational study. To investigate the effect of serum calcium levels on postoperative pain in patients undergoing abdominal surgery, and to determine whether changes in serum calcium levels are a risk factor for postoperative pain.

Detailed description

This study aimed to measure the total serum calcium and ionized calcium levels both before and after surgery. Additionally, NRS scores were recorded at different time points.

Interventions

  • Diagnostic test Peripheral venous blood
    Peripheral venous blood was collected before and after the surgery to measure the total serum calcium levels.
  • Diagnostic test Arterial blood
    Arterial blood was collected before anesthesia induction and after removal of the artificial airway to measure ionized calcium levels.

Primary outcome measures

  • The incidence of pain NRS score ≥6 within 48 hours after surgery [Time frame: From the end of the surgery to 48 hours after surgery]
Secondary outcome measures (8)
  • The maximum incisional pain score at 0-12h postoperatively [Time frame: From the end of the surgery to 12 hours after surgery]
  • The maximum incisional pain score at 12-24h postoperatively [Time frame: From 12hours to 24 hours after surgery]
  • The maximum incisional pain score at 24-48h postoperatively [Time frame: From 24 hours to 48 hours after surgery]
  • The maximum visceral pain score at 0-12h postoperatively [Time frame: From the end of the surgery to 12 hours after surgery]
  • The maximum visceral pain score at 12-24h postoperatively [Time frame: From 12 hours to 24 hours after surgery]
  • The maximum visceral pain score at 24-48h postoperatively [Time frame: From 24 hours to 48 hours after surgery]
  • Whether additional analgesia was administered within 48 hours after surgery [Time frame: From the end of the surgery to 48 hours after surgery]
  • Patient-controlled intravenous analgesia opioid consumption [Time frame: From the end of the surgery to 24 hours and 48 hours after surgery]

Eligibility criteria

Inclusion criteria

  • Aged 18-70 years old
  • American Society of Anesthesiologists Classification I-III
  • Patients undergoing elective abdominal surgery under general anesthesia
  • Patients participate voluntarily and sign an informed consent form

Exclusion criteria

  • Patients with a history of severe disease
  • Patients with chronic preoperative pain and/or long-term analgesic use
  • Patients with hearing disorders or verbal communication difficulties
  • Patients with psychiatric disorders or cognitive dysfunction
  • Patients requiring mechanical ventilation or ICU admission after surgery
  • Patients with a history of substance or alcohol abuse Patients who could not cooperate with the study for any reason

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Other

Study locations

China · 1 center
  • The Second Affiliated Hospital of Chongqing Medical University — Chongqing

Identifiers

NCT: NCT06957158 · Serum calcium levels and pain

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗