Intertransverse Process Block for Quality of Recovery Post-Open Hepatectomy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Intertransverse process block.
- Who it may be relevant to
- Registry conditions: Hepatectomy, Intertransverse Process Block, Quality of Recovery (QoR-15). Basic parameters: 18 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effect of Intertransverse Process Block on the Quality of Recovery Post-Open Hepatectomy: A Pilot Non-Randomised Study of Intervention
Overview
The study aims to assess the analgesic efficacy of the ITPB at the retro-SCTL space in patients undergoing major open hepatectomy surgery. This is assessed by: Primary Objective: Primary outcome measure: ● Assessing the quality of recovery 15 (QoR15) score at 24 and 48 hours Secondary outcome measure: * Number of anaesthetic and hypoesthetic dermatomes on the ventral and dorsal aspect of the thorax on both the sides at 30 minutes of block completion and during the post anaesthetic room (PACU) discharge * Assessing the 24-hour area under the curve of postoperative pain numerical rating score (NRS, 0-10) at rest and deep breathing or upon use of triflow. * Assessing the amount of postoperative morphine (mg) equivalent consumption at 24 and 48 hours * Time to discharge from High dependency unit (HDU) or Intensive care unit (ICU) Hypothesis: The investigators hypothesize that the application of ITPB targeting the retro-SCTL space in patients undergoing open hepatectomy will improve overall quality of recovery and pain score.
Interventions
- Procedure Intertransverse process block
The patient(s) will receive a pre-induction Intertransverse process block as pilot study
Primary outcome measures
- Quality of Recovery (QOR-15) [Time frame: 24 and 48 hours]
Secondary outcome measures (4)
- Dermatomal blockade on Thorax 30 minutes upon block completion [Time frame: Up to 30 minutes after block completion]
- 24 hours area under curve of postoperative pain score [Time frame: Up to 24 hours]
- Morphine consumption at 24 and 48 hours postoperatively [Time frame: At 24 and 48 hours postoperatively]
- Time to discharge from HDU / ICU [Time frame: Up to 5 days]
Eligibility criteria
Inclusion criteria
\- Adult patients aged 18-75 years of ASA I - III physical status classification undergoing open hepatectomy for benign or malignant liver lesion.
Exclusion criteria
- Patient refusal
- Patients who are unable to comprehend the QoR15 form
- Local or systemic infection
- Coagulopathy leading to absolute contraindication to regional anesthesia
- Contraindication to local anaesthetics (LA) such as LA allergy
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06957041 · CRE Ref. No. 2024.562