Recruiting NCT06953622
Establishment of a Clinical and Prognostic Follow-up Cohort of Migraine Patients With Patent Foramen Ovale
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Conservative treatment, Antipaletet drug, Patent Foramen Ovale Closure.
- Who it may be relevant to
- Registry conditions: Migraine, Patent Foramen Ovale. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
To establish a headache center in China that combines clinical, imaging and laboratory examinations, explore the feasible treatment options for migraine combined with patent foramen ovale, and search for the possible influencing factors, construct models that influence prognosis.
Interventions
- Drug Conservative treatment
Receive no antipaletet drug treatment and surgery - Drug Antipaletet drug
Use of antipaletet drugs. - Procedure Patent Foramen Ovale Closure
Receive the surgery of Patent Foramen Ovale
Primary outcome measures
- The changes of migraine attacks [Time frame: 3 months, 6 months, 1 year, 2 years and 3 years]
Eligibility criteria
Inclusion criteria
- Meet the diagnostic criteria for migraine in the International Classification of Headache (ICHD-3);
- Confirmation of patent foramen ovale through transthoracic echocardiography(TTE) or transesophageal echocardiography(TEE)/right heart contrast echocardiography
- Agree to participate in the study and sign the informed consent form.
Exclusion criteria
- Can not sign the informed consent form or cooperate with follow-up.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Peking University Third Hospital — Beijing
Identifiers
NCT: NCT06953622 · M2024296