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Recruiting NCT06953180

Epigenetics and NCD Prevention in Kazakhstan: Personalized Approaches and Biological Age Prediction

— Observational Cardiovascular Diseases (CVD) Type 2 Diabetes Chronic Respiratory Diseases Obesity (Disorder)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Genetic: DNA analysis.
Who it may be relevant to
Registry conditions: Cardiovascular Diseases (CVD), Type 2 Diabetes, Chronic Respiratory Diseases, Obesity (Disorder). Basic parameters: 18 years — 69 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Kazakhstan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Epigenetics and Prevention of Non-communicable Diseases in Kazakhstan: a Personalized Approach and Biological Age Prediction

Overview

This study aims to enhance personalized and preventive care for non-communicable diseases (NCDs) in Kazakhstan by examining epigenetic factors, predicting biological age and reproductive function using machine learning, and developing health improvement recommendations.

Interventions

  • Other Genetic: DNA analysis
    Investigation of telomere length (TL) and DNA methylation level analysis

Primary outcome measures

  • Accuracy of Machine Learning Model for Predicting Biological Age [Time frame: Within 10 months from start of data collection]
  • Accuracy of Reproductive Function Prediction Model [Time frame: Within 10 months from start of data collection]

Eligibility criteria

Inclusion criteria

  • Adults aged 18 to 69 years.
  • Residents of 17 regions of Kazakhstan.
  • Willingness to participate and provide informed consent.

Exclusion criteria

  • Age less than 18 years old or over 69 years old.
  • Failure to provide informed consent or incomplete participation in data collection procedures.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Other

Study locations

Kazakhstan · 1 center
  • Asfendiyarov Kazakh National Medical University — Almaty

Identifiers

NCT: NCT06953180 · BR27304987

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗