Comparison of Anterior Chamber Depth in High Myopes
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Anterior Chamber Depth. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Comparison of Anterior Chamber Depth Measured by Anterior Segment Optical Coherence Tomography , Ultrasound and Pentacam in High Myopes
Overview
This study aims to compare the accuracy and reliability of anterior chamber depth (ACD) measurements obtained using three imaging modalities: anterior segment optical coherence tomography (A-S OCT), ultrasound biomicroscopy (UBM), and the Pentacam Scheimpflug imaging system. The research focuses on high myopic patients and evaluates the consistency and correlation of these measurements with the degree of myopia.
Detailed description
The research is a cross-sectional, prospective, observational cohort study conducted in ophthalmological settings at Assiut University Hospital, Elforsan Center, and Tyba Center. It investigates the anterior chamber depth (ACD) in high myopes using three advanced diagnostic imaging tools:
Anterior Segment Optical Coherence Tomography (A-S OCT): A non-invasive imaging technique for high-resolution cross-sectional imaging of the anterior segment.
Ultrasound Biomicroscopy (UBM): An imaging method that uses high-frequency ultrasound to visualize anterior segment structures.
Pentacam HR (Scheimpflug Imaging System): A device that provides three-dimensional imaging of the anterior chamber.
The primary objective is to determine the mean differences in ACD measurements among these devices. Secondary objectives include assessing the correlation between ACD measurements and the degree of myopia, as well as evaluating the repeatability of measurements for each device.
Primary outcome measures
- Mean difference in ACD measurements between A-S OCT, UBM, and Pentacam. [Time frame: During the procedure]
Eligibility criteria
Inclusion criteria
- Patients aged 18 years or older
- High myopes with axial length >26mm or , and refractive error > -6 ,00 D
- Ability to fixate for OCT and Pentacam imaging
Exclusion criteria
- History of ocular surgery or trauma
- Presence of corneal pathology
- Active ocular inflammation
- Inability to fixate for imaging procedure
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Smith A, Johnson B, Lee C. Anterior chamber depth measurement in high myopia: A comparative analysis. J Cataract Refract Surg. 2021;47(5):612-620.
- Wan T, Ding X, Sun Y. Swept-source OCT for anterior segment imaging in high myopia. BMC Ophthalmol. 2021;21(1):62.
Identifiers
NCT: NCT06946043 · anterior chamber depth measure