Efficacy of Genicular Block on Total Knee Arthroplasty Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Genicular blocks (bupivakain), Patient Control Analgesia (PCA) Morphine group, Paracetamol (acetaminophen) + Diclofenac Sodium.
- Who it may be relevant to
- Registry conditions: Total Knee Anthroplasty, Genicular Nerves Block. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Assesment of Postoperative Analgesic Efficacy of Preoperatively Applied Genicular Block on Total Knee Arthroplasty: A Randomized Controlled Study
Overview
The aim of this study is to investigate the postoperative pain relieving effect of preoperative genicular block in total knee arthroplasty surgery. The main questions it aims to answer are: 1. Do visual analog scale (VAS) scores decrease in patients who underwent geniculate block? 2. Does opioid consumption decrease in patients who underwent geniculate block? Researchers will compare postoperative pain in patients who received genicular block with those who did not.One group of patients will be administered 0.25% bupivacaine with the geniculate block method. The other group will not undergo any intervention. Both groups will be administered intravenous morphine for postoperative analgesia.
Detailed description
Patients scheduled for knee arthroplasty will be randomly assigned into two groups. One group will receive a genicular nerve block prior to surgery , while the other group will not undergo any interventional procedure. The genicular nerve block will be administered in three quadrants around the knee, with each injection consisting of 5 mL of 0.25% Marcaine. All injections will be performed by investigator MA. Patient assessments will be conducted by investigator MO. Postoperative intravenous analgesia will be provided to both groups.
Interventions
- Drug Genicular blocks (bupivakain)
Genicular block is a regional analgesic technique performed with USG - Drug Patient Control Analgesia (PCA) Morphine group
this group consists of the patients no any intervention preoperatively and they will be given morfin with PCA (Patient controlled analgesia) and paracetamol 3x1000 mg intravenous and diclofenac 75 mg intramuscular (if needed) - Drug Paracetamol (acetaminophen) + Diclofenac Sodium
All patients are given paracetamol (3x1000 mg) and diclofenac (if needed)
Primary outcome measures
- Visual Analog Scale Measure [Time frame: 0-48 hours]
- opioid consumption [Time frame: 0-48 hours]
Eligibility criteria
Inclusion criteria
- Scheduled for unilateral and primary total knee arthroplasty
- Older than 18 years of age
Exclusion criteria
- Younger than 18 years
- Bilateral knee arthroplasty
- Revision case of knee arthroplasty
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Supportive care
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Wang T, Leng YF, Zhang Y, Kang YQ, Xue X, Zhang Y. [Preventive effects of ischemic postconditioning and penehyclidine hydrochloride on gastric against ischemia-reperfusion injury in rats]. Zhonghua Yi Xue Za Zhi. 2011 Apr 26;91(16):1130-5. Chinese. PMID 21609599
Identifiers
NCT: NCT06942702 · MersinUgenicular